… Mitochondria: RCAN1 has been shown to help maintain … Interestingly, mitochondria fusion
is increased in induced … that RCAN1 is critical to mitochondrial network maintenance in …

… analysis of the mitochondrial network supports the notion … mtDNA mutations and the imbalance
of mitochondria fusion, … Similar to other HSA21 genes, RCAN1/DSCR1 gene was found …

… a function of mitochondria, has been observed in Down syndrome (DS)… mitochondrial
dynamics, from fission/fusion mechanisms to … mitochondrial dynamics and maintains mitochondrial …

… and RCAN1 during heart development perturbs mitochondrial … HSA21-encoded Down
Syndrome Critical Region (DSCR) has … the mitochondria, while fused mitochondrial network is …

… existence of the Down syndrome critical region (DSCR). This … during cardiac development
before endocardial cushion fusion. The … RCAN1 depletion restores the mitochondrial network, …

… (RCAN1), also called the DS critical region gene 1 (DSCR1) (… RCAN1 helps maintain a
more fused mitochondrial network … expression level of Down Syndrome Critical Region 9 (DSCR9…

… regulator of calcineurin 1 (RCAN1) in the maturation stage [2]; however, its function in
enamel formation is unknown. RCAN1 (also called Down syndrome candidate region 1 (DSCR1)) …

… before endocardial cushion fusion. Its overexpression, due to the … the overexpression of
DYRK1A and RCAN1 genes in DS may be … consisted of genes coding for mitochondrial proteins …

… Down syndrome (DS, OMIM #190685) is a genetic neurodevelopmental disease that is …
mitochondrial biogenesis and fusion/fission dynamics also lead to bioenergetics defects, network …

… , which contains a fusion of the Mrpl39-Zbtb21 region including the … the regulator of calcineurin
1 (Rcan1) gene may be involved … was found to be involved in regulating the mitochondrial …