Currently available inhaled therapies in asthma and advances in drug delivery and devices

B Thomas, A Pugalenthi - Indian journal of pediatrics, 2022 - Springer
… (ICS), short-acting β 2 agonists (SABA), long-acting β 2 … In addition to improving drug delivery
to the airways, spacers … —jet nebulizers, ultrasonic nebulizers, mesh nebulizers, and smart …

[HTML][HTML] … of effectiveness of metered dose inhaler with spacer and jet nebulizer in children aged 5–14 years with acute exacerbation of asthma: A pilot randomized …

K Mittal, R Batra, A Khanna - Journal of Pediatric Critical Care, 2021 - journals.lww.com
… includes inhaled short-acting β2-agonists (SABA). The aim of … the device actuation and
inhalation due to lack of patient … the effectiveness of these two drug delivery systems in 100 …

Spacers versus Nebulizers in Treatment of Acute Asthma A Prospective Randomized Study in Preschool Children

MB Hamza, AI Harkan - The Egyptian Journal of Hospital Medicine, 2022 - journals.ekb.eg
… of children who use MDIs without devices, such as a spacers … some forgiveness in medication
delivery even when misused … The children were given either 4 ml of inhaled beta-2-agonist

[PDF][PDF] The use of metered-dose inhaler versus nebulization for the delivery of salbutamol in pediatric severe asthma exacerbations: A systematic review

KT Perez, BP MANDANAS-PAZ - … of the Philippine Children's Medical …, 2022 - pcmc.gov.ph
… of MDI with spacers versus nebulizers in drug delivery of … of salbutamol, a short-acting
beta-agonist (1). Recent randomized … nebulization and find the noise produced by the device as …

Metered‐dose inhalers vs nebulization for the delivery of albuterol in pediatric asthma exacerbations: A cost‐effectiveness analysis in a middle‐income country

CE Rodriguez‐Martinez… - Pediatric …, 2020 - Wiley Online Library
… (spacers) compared to nebulizers for the delivery of beta2-agonists for acute asthma 9 that
… costs of medications and delivery devices for each of the two modes of delivery of albuterol, …

Clinical Efficacy of Salbutamol Delivered Via Nebulizer Versus Metered Dose Inhaler with Spacer and Mask in Wheezing Children

NA Sher, S Lal, MS Raza, A Ahsan, S Larik, R Sangi… - HIV Nursing, 2023 - hivnursing.net
… wheezing children using a metered close inhaler and a nebulizer. … of beta-2 agonists
administered by metered-dose inhaler (MD… P Advances in pulmonary drug delivery devices for the …

Aerosolized drug delivery in awake and anesthetized children to treat bronchospasm

N Anderson, S Clarke… - Pediatric …, 2022 - Wiley Online Library
… , a non-selective adrenergic agonist—to reduce … drug product (eg, nebulizers, spacers).
Clinicians have to keep in mind that device-only products are not required to conform with drug-…

Commercial valved spacers versus home-made spacers for delivering bronchodilator therapy in pediatric acute asthma: a cost-effectiveness analysis

CE Rodríguez-Martínez, MP Sossa-Briceño… - … of Asthma, 2021 - Taylor & Francis
delivered via nebulization, the advantages of delivering … -2 agonists delivered through MDI
using home-made spacers with … spacers, a common and widely-used device for delivering

[HTML][HTML] The use of inhaler devices in children

RH Moore, RA Wood - Wolters Kluwer [accessed 20 Oct 2023], 2021 - medilib.ir
… that adding a spacer improves drug delivery or efficacy as … beta agonists via pMDI with
spacer is at least as effective as, and possibly superior to, delivery of medication by jet nebulizer

Prehospital β₂-agonist administration via spacer versus nebuliser

CD Christiansen, MTK Nielsen, JL Søltoft… - Danish Medical …, 2024 - vbn.aau.dk
… One explanation may be better active drug delivery to … study of patients treated with inhaled
β2-agonists in the … following the transition from nebuliser to spacer as the delivery device for …