… optimisation by means of dual bronchodilation with tiotropium/olodaterol, and present new
data … We also examine the relationship between reducing activity-related breathlessness, the …

… that addresses activity-related breathlessness can help … Umeclidinium/vilanterol has
been shown to reduce breathlessness … Furthermore, dual bronchodilation with tiotropium/olodaterol …

… Breathlessness and COPD-associated symptoms cause patients to reduce PA, leading to a
… the FDC of tiotropium/olodaterol would be those patients with lower physical functioning at …

… disease exacerbations with tiotropium + olodaterol … and include mono-bronchodilation or
dual bronchodilation (short- and … time and reduced physical activity–related dyspnea with or …

… Moreover, a lower level of physical activity has the strongest … -acting dual bronchodilation
(LAMA + LABA) treatment with … based on the modified Medical Research Council dyspnea …

… (lower limit FEV … dyspnoea severity compared with tiotropium alone, without compromising
patient safety. These results support the use of dual bronchodilation with tiotropium/olodaterol …

… 40 years who were prescribed tiotropium/olodaterol 5/5 μg via … condition, the severity of
dyspnea according to the mMRC … to a decrease in the number of CCQ points by more than 0.4 …

… Dual bronchodilator reduced activity-related dyspnea, as judged by the … tiotropium/olodaterol
versus tiotropium to achieve a clinically significant improvement in activity-related dyspnea…

… Persistent airflow limitation and dyspnoea may reduce … inactive patients and daily
activity-related energy expenditure, and … -analysis, where tiotropium/olodaterol was the most …

… such as activity-related breathlessness and inspiratory … treatment over monotherapy for
CID, further prospective studies … of dual bronchodilation can reduce the risk of future disease …