Matrix metalloproteinases as biomarkers of atherosclerotic plaque instability

W Olejarz, D Łacheta… - International journal of …, 2020 - mdpi.com
… MMPs contribute to intimal thickening and vessel wall remodeling in atherosclerosis by …
MMPs degrade ECM and facilitate VSMCs migration into the intima. Studies have shown that …

The role of matrix metalloproteinases in the progression and vulnerabilization of coronary atherosclerotic plaques

D Opincariu, N Rat, I Benedek - Journal of Cardiovascular …, 2021 - sciendo.com
… to provide a summary on the role of serum matrix metalloproteinases in the process of initiation…
Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic

The roles of matrix metalloproteinases and their inhibitors in human diseases

GA Cabral-Pacheco, I Garza-Veloz… - International journal of …, 2020 - mdpi.com
… -9 plays a role in atherosclerosis development, and both … and inflammatory cells within the
intima of large arterial walls, … and proteoglycan, giving it a dual role in ECM destruction in RA […

The contribution of matrix metalloproteinases and their inhibitors to the development, progression, and rupture of abdominal aortic aneurysms

G Atkinson, R Bianco, K Di Gregoli… - Frontiers in …, 2023 - frontiersin.org
… often have atherosclerosis, and intimal atherosclerosis is … findings in humans; the dual role
of MMPs and the requirement to … Matrix metalloproteinases (MMPs), also known as matrixins, …

The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?

M Irqsusi, LA Dong, FR Rodepeter, R Ramzan… - Biomedicines, 2024 - mdpi.com
intima area at all. TIMP 1 and TIMP 2 distribution increases from the lumen of the vessel outward
in the wall layers of the aorta. In the case of arteriosclerotic changes, intima … a matrixin, a …

Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and Disease

S Molière, A Jaulin, CL Tomasetto… - International Journal of …, 2023 - mdpi.com
… Altogether, MMP3 seems to play a dual role in adipose tissue biology; it negatively controls
… complex role of MMPs and their inhibitors in vascular intima thickening and atherosclerosis

[HTML][HTML] Proteomic analysis of the extracellular matrix of human atherosclerotic plaques shows marked changes between plaque types

LG Lorentzen, K Yeung, N Eldrup, JP Eiberg… - Matrix Biology Plus, 2024 - Elsevier
… This analysis clearly indicates two strong and significant network clusters of over-abundant
matrix metalloproteinases (MMPs 7, 8 and 9), together with a common inhibitor of these (…

The association of matrix metalloproteinases with chronic kidney disease and peripheral vascular disease: a light at the end of the tunnel?

M Provenzano, M Andreucci, C Garofalo, T Faga… - Biomolecules, 2020 - mdpi.com
… carotid Intima-Media Thickness (… role in the link between metalloproteinases, CKD, and
PVD is indicated by NGAL. It has been shown that NGAL levels are increased in atherosclerosis

A Review on the Relationship between Matrix Metalloproteinases (MMPS) and their Natural Inhibitors (Tissue Inhibitors of Matrix Metalloproteinases [Timps]) and the …

MNAA Rahman, AF Othman - IIUM Medical Journal Malaysia, 2021 - journals.iium.edu.my
… The first endogenous matrixins, labelled as tissue inhibitor of metalloproteinases (TIMPs), …
prevent significant intimal hyperplasia after angioplasty and stenting in atherosclerotic animal …

Plasma matrix metalloproteinases (MMP-2 and MMP-9) as prognostic biomarkers in coronary heart disease.

T Marynenko, T Halenova, N Raksha… - Minerva …, 2022 - search.ebscohost.com
… increased expression of matrix metalloproteinases and matrix degrading activity in
vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994;94:2493–503. 16. …