[HTML][HTML] The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?
M Irqsusi, LA Dong, FR Rodepeter, R Ramzan… - Biomedicines, 2024 - mdpi.com
… intima area at all. TIMP 1 and TIMP 2 distribution increases from the lumen of the vessel outward
in the wall layers of the aorta. In the case of arteriosclerotic changes, intima … a matrixin, a …
in the wall layers of the aorta. In the case of arteriosclerotic changes, intima … a matrixin, a …
[HTML][HTML] Role of oncostatin-M in ECM remodeling and plaque vulnerability
P Patel, V Rai, DK Agrawal - Molecular and Cellular Biochemistry, 2023 - Springer
… role in the development and progression of atherosclerosis, … and its role in ECM remodeling
after an intimal injury is largely … Matrix metalloproteinases (MMPs), a group of enzymes that …
after an intimal injury is largely … Matrix metalloproteinases (MMPs), a group of enzymes that …
[HTML][HTML] Plasma levels of matrix metalloproteinase-9 are elevated in individuals with hypertensive crisis
FM Valente, DO de Andrade… - BMC Cardiovascular …, 2020 - Springer
… and proliferation with resulting thickening of the vascular wall … pathways such as matrix
metalloproteinases, especially … role in cell migration and infiltration in the atherosclerotic process […
metalloproteinases, especially … role in cell migration and infiltration in the atherosclerotic process […
[HTML][HTML] Multifaceted role of matrix metalloproteinases in neurodegenerative diseases: Pathophysiological and therapeutic perspectives
… Although the etiology and potential causes of NDs remain widely indefinable, matrix
metalloproteinases (MMPs) evidently have a crucial role in the progression of NDs. MMPs, a protein …
metalloproteinases (MMPs) evidently have a crucial role in the progression of NDs. MMPs, a protein …
[HTML][HTML] Molecular interactions between vascular smooth muscle cells and macrophages in atherosclerosis
J Beck-Joseph, S Lehoux - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
… intimal thickenings (PITs) are believed to characterize the onset of atherosclerosis and
develop from diffuse intimal … significantly suppressed intimal thickening and macrophage …
develop from diffuse intimal … significantly suppressed intimal thickening and macrophage …
[HTML][HTML] Parecoxib improves atherosclerotic plaque stability by suppressing inflammation and inhibiting matrix metalloproteinases production
C Gong, Y Qi, Y Xu, X Tang, F Liang, L Chen - Biomedicine & …, 2021 - Elsevier
… Atherosclerosis is a chronic progressive disease that is initiated by the pathologic intimal
thickening of coronary arteries., which are composed of vascular smooth muscle cells (VSMC) …
thickening of coronary arteries., which are composed of vascular smooth muscle cells (VSMC) …
Kruppel-Like Factor 2 and Matrix Metalloproteinases in the Context of Vasculature
S Anderson, D Barthels, H Das - Matrix Pathobiology and Angiogenesis, 2022 - Springer
… plaques begin to form when macrophages in the intimal layer of an artery engulf oxidized …
central roles: angiogenesis, atherosclerosis, and clotting, and examined the different roles that …
central roles: angiogenesis, atherosclerosis, and clotting, and examined the different roles that …
[HTML][HTML] Fibrotic signaling in cardiac fibroblasts and vascular smooth muscle cells: the dual roles of fibrosis in HFpEF and CAD
JC Bachmann, SJ Baumgart, AK Uryga, MH Bosteen… - Cells, 2022 - mdpi.com
… myocardial stiffening and atherosclerotic plaque stability add … NFκB also upregulates the
matrix metalloproteinase (MMP)-9 … /synthetic VSMCs causes intimal thickening and plaque …
matrix metalloproteinase (MMP)-9 … /synthetic VSMCs causes intimal thickening and plaque …
[HTML][HTML] Sex-related differences of matrix metalloproteinases (MMPs): new perspectives for these biomarkers in cardiovascular and neurological diseases
A Trentini, MC Manfrinato, M Castellazzi… - Journal of Personalized …, 2022 - mdpi.com
… the architecture of atherosclerotic plaque helping its disruption [40]. However, their role is not
just … , myocardial infarction, atherosclerosis, hypertension, and cardiomyopathies (Table 1). …
just … , myocardial infarction, atherosclerosis, hypertension, and cardiomyopathies (Table 1). …
Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis
G Testa, E Staurenghi, S Giannelli, B Sottero… - Biochimie, 2021 - Elsevier
… activity of matrix metalloproteinases (MMPs) involved in extracellular matrix remodeling and
… SMC migration in the intima by MMP-14 activation, plays a key role in vascular remodeling […
… SMC migration in the intima by MMP-14 activation, plays a key role in vascular remodeling […