… played by ubiquitin and ubiquitin-like proteins in the equilibrium between synapse physiology
and neurodevelopment disorders [83], the role of MeCP2 ubiquitination and sumoylation …

… Ubiquitin proteasome system … identified down-regulation of 12 of 39 proteasome subunit
genes in schizophrenia. The signal of proteasome subunits down-regulation was replicated in …

… with a SUMO (small ubiquitin-like modifier) E3-ligase activity, … patients with autism and
schizophrenia. Moreover, Rhes … to autism spectrum disorder (ASD) and schizophrenia [47-49]…

… RXR are implicated in mental disorders, including schizophrenia. Reduced expression of
RXRA and PPARA was observed in the hair follicle cells from individuals with schizophrenia [ …

… of the ubiquitin-like proteasome system (UPS… proteasome dysfunctions. UPS is a very
important feature of the proteostasis network. Therefore, to verify whether ubiquitin-like proteasome …

… Besides ubiquitin (Ub), humans have a set of ubiquitin-like proteins (UBLs) that can also
covalently modify target proteins. To date, less is known about UBLs than Ub and even less is …

… Ubiquitin-fold modifier 1 (UFM1) is a newly identified ubiquitin-like protein that has been …
COL2A1, the downstream target of SOX9, is linked to skeletal disorders. Therefore, UfBP1 …

… Liver dysfunction occurs in the early stages of sepsis, and … shuttles it to the proteasome via
its ubiquitin-like (UBL) domain … to human disease such as schizophrenia and virus infection […

… out of the mitochondria and trigger UPR mt by ATP-binding cassette subfamily B member
10 (Abcb10) 36, 37, whereas defective proventriculus1 (DVE1) and the small ubiquitin-like …

… ubiquitin-like modifier (SUMO) [9, 12, 13]. In addition to PD and HD, Rhes is associated with
tauopathy and mental disorders. … participate in diverse brain disorders remains unclear. Our …