The Effects of Hyperlipidemia on Regulatory T Cells

M Hyde - 2021 - search.proquest.com
… the periphery from a naïve CD4 T cell. IL-2 along with TGF-β induces naive CD4+ CD25- T
cells to transform into CD4+ CD25+ T cells and express FoxP3. Naïve CD4 T cell can also be …

Metabolic alterations impair differentiation and effector functions of CD8+ T cells

A Bensussen, MA Santana… - Frontiers in …, 2022 - frontiersin.org
… to explore the potential effect of metabolic alterations such as … , dyslipidemia, and diabetes
on CD8+ T cell differentiation. … + T cell functions in the context of the metabolic dysregulation

THE IMPACT OF CLEC4A4 DEFICIENCY ON CARDIOMETABOLIC DISEASES

R Bellini - 2024 - air.unimi.it
… and maturation of T lymphocytes in vivo. It activates and facilitates commitment to certain T
cell lineages, promotes differentiation, and supports the survival of cells in the thymus within …

[HTML][HTML] T cells expressing the lupus susceptibility allele Pbx1d enhance autoimmunity and atherosclerosis in dyslipidemic mice

W Li, AS Elshikha, C Cornaby, X Teng, G Abboud… - JCI insight, 2020 - ncbi.nlm.nih.gov
… mechanisms of CD4 + T cell dysregulation between SLE and … cells, we next investigated
directly the effect of dyslipidemiacells from total CD4 + T cells under in vitro Tfh differentiation

Advances in T cells based on inflammation in metabolic diseases

W Yu, C Li, D Zhang, Z Li, P Xia, X Liu, X Cai, P Yang… - Cells, 2022 - mdpi.com
Dysregulation of gut microbiota and pro-opio-melano-cortin … In this review, we will describe
the effect on T cells in the … , then differentiate into two major T cell lineages with different …

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells

…, R Nuboer, B Vastert, CK van der Ent, B van't Land… - Scientific Reports, 2021 - nature.com
… clustering within lipid rafts, dysregulation of lipid raft turnover may … The uptake of lipoproteins
by T cells can affect their … not associated with inflammation and dyslipidemia 32 . Vice versa, …

B cells and atherosclerosis: A HIV perspective

LM Obare, RH Bonami, AC Doran… - Journal of Cellular …, 2024 - Wiley Online Library
… immune activation and dysregulation, influences B cells in the … activation and differentiation
of pro‐inflammatory T cells and … dysregulation, altered cholesterol metabolism, direct effects

Role of Impaired Lipid Metabolism and Immune Dysregulation in the Pathogenesis of Cardiovascular Disease

S Su - 2022 - search.proquest.com
… subset of CD4+ T cells, natural regulatory T cells (Tregs), … and those formed by differentiation
of naive T cells outside the … effects of SRSF1 deficiency on the function of CD8+ T cells. …

[HTML][HTML] Medical treatment can unintentionally alter the regulatory T-cell compartment in patients with widespread pathophysiologic conditions

SN Copsel, TR Malek, RB Levy - The American journal of pathology, 2020 - Elsevier
effects on Tregs have been less studied. For instance, this hormone promoted in vitro
differentiation of naive cord blood fetal T cells… multiple cytokines are dysregulated and thus …

Inflammation in HIV and its impact on atherosclerotic cardiovascular disease

LM Obare, T Temu, SA Mallal, CN Wanjalla - Circulation research, 2024 - Am Heart Assoc
… may contribute to dyslipidemia due to direct effects of antiviral … triglycerides presumed to
be from dysregulated clearance. In a … role of γδ T cells, as many aortic γδ T cells in this study …