Modulation of miR-192/NF-κB/TGF-β/E-cadherin by thymoquinone protects against diethylnitrosamine/carbon tetrachloride hepatotoxicity

H Ashour, ME Farghaly, AA Khowailed… - Physiology …, 2022 - akjournals.com
… carcinogenesis, and it may regulate the expression of miR-192 and E-cadherin and the
TNF-α/L6/… 4, we identified a novel mechanism of thymoquinone for the early prevention of hepatic …

Small extracellular vesicles containing miR-192/215 mediate hypoxia-induced cancer-associated fibroblast development in head and neck squamous cell carcinoma

G Zhu, B Cao, X Liang, L Li, Y Hao, W Meng, C He… - Cancer Letters, 2021 - Elsevier
… role and mechanism of sEVs in regulating CAF … independent animals in each group, *P <
0.05. (E) The xenograft tumor tissues were measured for E-cadherin and Vimentin expression

KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2

L Sun, X Zhou, Y Li, W Chen, S Wu… - Cell Adhesion & …, 2020 - Taylor & Francis
… Furthermore, we detected the expression of E-cadherin and vimentin by … Most importantly,
we explored the mechanisms by which KLF5 and p53 coordinately regulate EMT. EMT is a …

Review on correlation between MiRNA-192 and the pathogenesis of diabetes and treatment progress of diabetic nephropathy.

W Liu, H Jiang, S Song… - Journal of Hainan Medical …, 2021 - search.ebscohost.com
regulatory loop is one of the mechanisms for the development of diabetic nephropathy [14]. …
in E - cadherin expression is reduced, the kidney in diabetic rats,TGF - β can be expressed

miR-192-5p suppresses uterine receptivity formation through impeding epithelial transformation during embryo implantation

J Liang, D Cao, X Zhang, L Liu, Q Tan, S Shi, K Chen… - Theriogenology, 2020 - Elsevier
… Subsequently, the potential mechanism underlying the regulation of E-cadherin expression
… an E-box suppressor that downregulates E-cadherin transcription by binding to its promoter […

Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric …

X Zhang, Y Peng, Y Yuan, Y Gao, F Hu, J Wang… - Cell Death & …, 2020 - nature.com
… , molecular mechanisms, and clinical impact of miR-192/215/… (E-cadherin, Snail, MMP9,
Vimentin, and ZEB1) regulated by … SET8 induced replication-independent senescence in GC. …

Rotavirus-Mediated Suppression of miRNA-192 Family and miRNA-181a Activates Wnt/β-Catenin Signaling Pathway: An In Vitro Study

A Banerjee, M Chawla-Sarkar, A Mukherjee - Viruses, 2022 - mdpi.com
… The mean of at least two independent experiments plus the … revealed that the combined effect
of miR-192/215 and miR-181a could … Inhibition of cell cycle arrest is a common mechanism

Overexpression of miR-192 in Fibroblasts accelerates wound healing in diabetic rats

F Karam, M Sayadi, S Dadi, GA Sarab - 2024 - researchsquare.com
… Wang B et al (2010) E-cadherin expression is regulated by miR-192/215 by a mechanism
that is independent of the pro brotic effects of transforming growth factor-β. Diabetes 59(7):…

[HTML][HTML] Promoter methylation-mediated silencing of the MiR-192-5p promotes endometrial cancer progression by targeting ALX1

J Ni, W Tian, S Liang, H Wang… - International Journal of …, 2021 - ncbi.nlm.nih.gov
… Nevertheless, the exact molecular mechanisms … of seven groups in three independent
experiments. In each experiment, … (g) MMP2, MMP9, VEGF, E-cadherin and Vimentin expression, …

Interplay between p53 and non-coding RNAs in the regulation of EMT in breast cancer

S Parfenyev, A Singh, O Fedorova, A Daks… - Cell death & …, 2021 - nature.com
regulation often involves interactions of miRNAs with lncRNAs. In this review, we present a
detailed overview of miRNA/lncRNA-dependent mechanisms … the expression of E-cadherin. It …