Discovery of RC-752, a Novel Sigma-1 receptor antagonist with antinociceptive activity: a promising tool for fighting neuropathic pain
… the swim bladder was not well inflated, and oedema was evident. … related to a potentially
recoverable developmental delay or … The formalin test was chosen as a tonic pain model for the …
recoverable developmental delay or … The formalin test was chosen as a tonic pain model for the …
Delta-and mu-opioid pathways are involved in the analgesic effect of Ocimum basilicum L in mice
AH Bae, G Kim, GH Seol, SB Lee, JM Lee… - Journal of …, 2020 - Elsevier
… The solvent delay time of mass spectrometer was 3 min with m/… that BEO reduced
carrageenan-induced edema and pyrexia … Antinociceptive activities of the methanol extract of the …
carrageenan-induced edema and pyrexia … Antinociceptive activities of the methanol extract of the …
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design
R Turnaturi, S Piana, S Spoto, G Costanzo, L Reina… - Molecules, 2024 - mdpi.com
… formalin test, SLE and fruticuline A significantly reduced the frequency of paw licking during
the first and second phases and decreased edema… but delayed, effect in the hot-plate test. …
the first and second phases and decreased edema… but delayed, effect in the hot-plate test. …
[PDF][PDF] Antinociceptive and antiinflammatory studies on Tradescantia zebrina
… compromise the immune system, cause infections, and delay the diagnosis and treatment of
… of the formalin test.Based on our results from the carrageenan-induced paw edema test, the …
… of the formalin test.Based on our results from the carrageenan-induced paw edema test, the …
Acidosis-related pain and its receptors as targets for chronic pain
CH Hung, Y Chin, YO Fong, CH Lee, DS Han… - Pharmacology & …, 2023 - Elsevier
… pain research and clinical pain diseases, thus helping with better understanding the acid-related
pain … potential therapeutic roles via the mechanism of acid-mediated antinociception. …
pain … potential therapeutic roles via the mechanism of acid-mediated antinociception. …
Venlafaxine HCl encapsulated in niosome: green and eco-friendly formulation for the management of pain
… The delay time for reactions to pain stimulation was then … -inflammatory and antinociceptive
action in the formalin test (22)… of 0.333 for edema and erythema which was much smaller than …
action in the formalin test (22)… of 0.333 for edema and erythema which was much smaller than …
[HTML][HTML] Chemical composition, antioxidant, anti-inflammatory and antinociceptive activities of the ethanol extract of ripe fruits of Solanum lycocarpum St. Hil …
MG Morais, AA Saldanha, JPC Rodrigues… - Journal of …, 2020 - Elsevier
… Pain involves mechanisms related to the response of the … effect observed in the first phase
of the formalin test. … potential, provoking the reduction of ear edema induced by chroton oil and …
of the formalin test. … potential, provoking the reduction of ear edema induced by chroton oil and …
Anti-inflammatory and antinociceptive activities of a phenylpropanoid-enriched fraction of Duguetia furfuracea
… Moreover, the in vivo antinociceptive effect was assayed using the formalin test and …
Treatment with the EFDf also resulted in significant paw oedema reduction in the … Full size image …
Treatment with the EFDf also resulted in significant paw oedema reduction in the … Full size image …
Micro-and nanocarriers for pain alleviation
A da Silva, S Lepetre-Mouelhi, P Couvreur - Advanced Drug Delivery …, 2022 - Elsevier
… inflammation levels is highly correlated to pain intensity, publications … of NPs in the dorsal
root ganglion, Prolonged antinociception … ) / Measurement of the paw edema thickness In vivo …
root ganglion, Prolonged antinociception … ) / Measurement of the paw edema thickness In vivo …
Anti-inflammatory activity of Cleome ciliata leaf Schumach & Thonn. in acute and chronic inflammatory models using rodents
… effect against formalin-induced arthritis, reducing paw size at … further observed for signs of
delayed toxicity after two weeks [14]. … dextran-induced paw oedema is principally mediated by …
delayed toxicity after two weeks [14]. … dextran-induced paw oedema is principally mediated by …