Emerging approaches to improve allogeneic hematopoietic cell transplantation outcomes for nonmalignant diseases

Z DeFilipp, M Hefazi, YB Chen… - Blood, The Journal of …, 2022 - ashpublications.org
… malignant cells that persist after conditioning, conventionally … engraftment compared with
unmanipulated grafts. Novel … served with genetically modified autologous graft strategies (…

Hematopoietic Stem Cell Transplantation an Alternative to Treat Crohn's Disease

MA Ruiz, M Rovira, E Ricart, RL Kaiser… - … Autoimmune Diseases, 2021 - taylorfrancis.com
persistent mixed chimerism contributed to 5 years of disease-… complete remission after
unmanipulated PBPC autotransplant… of Crohn disease after autologous stem cell transplantation …

Haploidentical stem cell transplantation in lymphomas—expectations and pitfalls

J Mariotti, S Bramanti, A Santoro… - Journal of Clinical …, 2020 - mdpi.com
… by the persistence of a not negligible rate of non-relapse … supported first by the evidence of
a reduced incidence of relapse … They concluded that risk of GvHD after unmanipulated DLI in …

Transcriptomic analysis of immune cell populations after allogenic and autologous Hematopoietic Stem Cells Transplantation HSCT in hematological cancers

A Lawag - 2023 - search.proquest.com
… germ cell tumors and certain autoimmune diseases. … When unmanipulated bone marrow
(BM) or umbilical cord blood (… -versus-host disease (GVHD), this dysfunction can persist for as …

Autologous Hematopoietic Stem Cell Transplantation in Stiff Person Spectrum Disorder

Z Yasiry, RK Burt, B Sharrack - … for Autoimmune Diseases, 2021 - taylorfrancis.com
… rigidity, recurrent falls, muscle spasms and anxiety disorder/… to years to objective persistent
stiffness and rigidity, caused byUnmanipulated peripheral blood stem cells were infused …

The role of the thymus in allogeneic bone marrow transplantation and the recovery of the peripheral T-cell compartment

E Velardi, E Clave, LCM Arruda, F Benini… - Seminars in …, 2021 - Springer
… GvHD (aGvHD) in unmanipulated haplo-HSCT thanks to the … recovery after HSCT as reported
in the autologous setting [21… of increased risks of disease progression or relapse [57]. The …

Long term outcomes of the French ASTIS systemic sclerosis cohort using the global rank composite score

N Ait Abdallah, M Wang, P Lansiaux… - Bone Marrow …, 2021 - nature.com
… chronic systemic autoimmune disease with high disease-… and infused unmanipulated
peripheral blood stem cells (… until death from any cause or persistent major heart, lung, or kidney …

Hematopoiesis and immune reconstitution after CD19 directed chimeric antigen receptor T‐cells (CAR‐T): A comprehensive review on incidence, risk factors and …

E Galli, A Fresa, S Bellesi, E Metafuni… - European Journal of …, 2024 - Wiley Online Library
… noticed in terms of survival or disease relapse. In the smaller … autologous stem cells or full
allogeneic hematopoietic stem … with a syndrome of persistent cytopenias after CAR-T cell …

Immune Suppression in Allogeneic Hematopoietic Stem Cell Transplantation

TF Michniacki, SW Choi, DC Peltier - Pharmacology of …, 2021 - Springer
… In contrast to autologous HSCT, the stem cell graft in … of female donors, unmanipulated
peripheral blood stem cell grafts … In addition, a small subset of patients may have persistent B cell …

Cell‐based therapies for the treatment of rheumatoid arthritis

MZ Moghaddam, MJ Mousavi… - … and Disease, 2023 - Wiley Online Library
autoimmune disorder, affect autologous connective tissues … and another group received
unmanipulated HSCs. The results … , manufacturing, and persistence must be confirmed for CAR-…