Lung imaging in COPD Part 2: emerging concepts

S Raoof, M Shah, S Braman, A Agrawal, H Allaqaband… - Chest, 2023 - Elsevier
… and the estimated blood volume contained in blood vessels with … It can provide regional
information on airflow in the lung … use in the lungs, 18 F-fludeoxyglucose PET has been explored …

Definition and clinical evaluation of a recruiting airway pressure based on the specific lung elastance in anesthetized dogs

J Araos, L Lacitignola, C Acquafredda, C DiBella… - Veterinary Anaesthesia …, 2021 - Elsevier
… tissue; however, hyperinflation was observed in all lung regions. The net alveolar … and
nonaerated lung tissue in all regions. Further studies should evaluate the impact of animal size, …

Placental vascular alterations are associated with early neurodevelopmental and pulmonary impairment in the rabbit fetal growth restriction model

I Valenzuela, D Basurto, Y Regin, A Gie… - Scientific reports, 2022 - nature.com
… trials after promising results in animal models. Most of these … Brain region volumes and
diffusion metrics were obtained … Before lung function tests, two deep inflation maneuvers were …

Using in vivo respiratory-gated micro-computed tomography imaging to monitor pulmonary side effects in 10 MV flash and conventional radiotherapy

X Ren, L Egoriti, N Esplen, S Rädel… - Medical Imaging …, 2023 - spiedigitallibrary.org
… Numerous FLASH-RT animal studies have verified a reduction … the lungs deflated (end
expiration) and at the peak of inflation (… the lung volume and CT numbers with a seeded region

Thoracic Imaging: Ventilation/Perfusion

HJ Hwang, SM Lee, JB Seo - Spectral Imaging: Dual-Energy, Multi-Energy …, 2022 - Springer
… (PET) have been used to evaluate and visualize the … Lung perfusion or pulmonary
blood volume (PBV) image is … The regional lung perfusion change on PBV map is matched …

Monitoring lung injury severity and ventilation intensity during mechanical ventilation

E Rezoagli, JG Laffey, G Bellani - Seminars in Respiratory and …, 2022 - thieme-connect.com
regions during cyclic tidal ventilation at low lung volumes (ie, … mL of blood over changes in
CO 2 and O 2 partial pressure. … increased the lung density by decreasing hyperinflation (dark …

Computational lung modelling in respiratory medicine

S Neelakantan, Y Xin, DP Gaver… - Journal of The …, 2022 - royalsocietypublishing.org
… in saline-filled lungs when compared with air inflation, due to … radioactivity in regions with
poor aeration in the PET scan. … However, lung tissues have low proton density and also yield …

Application-specific approaches to MicroCT for evaluation of mouse models of pulmonary disease

EF Redente, KW Kopf, AN Bahadur, A Robichaud… - Plos one, 2023 - journals.plos.org
… assessments of lung health and disease in small animal models. … A deep lung inflation to 30
cmH 2 O was performed over 3 … of the PATS task list generated regions of interest (ROI) used …

Development of a method to measure regional perfusion of the lung in anesthetized ponies using computed tomography angiography and the maximum slope model

A Auckburally, G Nyman, MK Wiklund… - … Veterinary Research, 2022 - Am Vet Med Assoc
… The endotracheal tube was connected to a large animal … in aerated lung regions as a
gradual increase in CT density … owing to effects on flow characteristics following lung inflation.…

Precision medicine using simultaneous monitoring and assessment with imaging and biomarkers to manage mechanical ventilation in ARDS

M Abbott, Y Li, L Brochard, H Zhang - Intensive Care Research, 2023 - Springer
… , including both animal models and human studies, to examine the … and regional lung
recruitment before changes in global … at all levels of PEEP, with hyperinflation measured by CT …