Human genetic susceptibility to hepatitis B virus infection

J Xu, Q Zhan, Y Fan, Y Yu, Z Zeng - Infection, Genetics and Evolution, 2021 - Elsevier
… of HBV infection, namely chronic (persistent) HBV infection and … , including mutations in
human leukocyte antigens (HLAs), … related to the human susceptibility to HBV infection. Among …

Association among cytokine profiles of innate and adaptive immune responses and clinical-virological features in untreated patients with chronic hepatitis B

Y Gu, Y Lian, Q Zheng, Z Huang, L Gu, Y Bi, J Li… - BMC Infectious …, 2020 - Springer
… the absence of an association regarding IFN-γ-secreting … effect to produce antiviral cytokines.
The detailed analysis of the noncytolytic control of viral infection derived from CHB patients

[HTML][HTML] … augments hepatitis B surface antigen clearance vs continuous nucleos (t) ide analog monotherapy in Chinese patients with chronic hepatitis B and hepatitis B …

FP Wu, Y Yang, M Li, YX Liu, YP Li… - World Journal of …, 2020 - ncbi.nlm.nih.gov
chronic hepatitis B patients with hepatitis B surface antigen levels ≤ 1500 IU/mL, hepatitis B
e antigen-negative and hepatitis B virus-… on the management of hepatitis B virus infection. J …

[HTML][HTML] Review of current and potential treatments for chronic hepatitis B virus infection

E Tsai - Gastroenterology & Hepatology, 2021 - ncbi.nlm.nih.gov
… : Chronic hepatitis B virus (HBV) infection remains a major global health burden. Millions of
people are at risk for complications of chronic HBV infection… for HBV infectioninterferon and …

Changes in the cytokine profiles of patients with chronic hepatitis B during antiviral therapy

MH Li, HH Lu, QQ Chen, YJ Lin, Z Zhan, LU Yao… - Biomedical and …, 2021 - Elsevier
Interferon can not only play a direct role in viral replication but also stimulate immune cell …
virusinfected liver cells. NA mainly inhibits viral replication and has no immunostimulatory effect

Immune mechanisms underlying hepatitis b surface antigen seroclearance in chronic hepatitis b patients with viral coinfection

S Wu, W Yi, Y Gao, W Deng, X Bi, Y Lin… - Frontiers in …, 2022 - frontiersin.org
chronic hepatitis B virus infection, the human body may also be coinfected with other
hepatophilic or non-hepatophilic viruses… HCV infected hepatocytes through human leukocyte

[HTML][HTML] Anti-viral effect in chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase

Q Zhao, K Liu, X Zhu, L Yan, Y Ding, Y Xu, S Lou… - Antiviral Research, 2020 - Elsevier
… In our current study, PEG-IFN treated CHB patients had … that the CHB patients treated with
PEG-IFN who had elevated ALT … ) than overall mean HBsAg decline in entire PEG-IFN group. …

Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection

E Aliabadi, M Urbanek-Quaing, B Maasoumy, B Bremer… - Gut, 2022 - gut.bmj.com
… cells were assessed in human leukocyte antigen (HLA)-A*02 patients (n=35). In addition,
in vitro responsiveness to anti-programmed cell death-ligand 1 (anti-PD-L1) was investigated. …

… Human Interferon α‐2b on Negative Conversion Rate, Liver Function, Immune Status, and Drug Safety in Patients with Chronic Hepatitis B: A Systematic Review and …

H Zhang, J Xian, Y Li, L Xiao… - … and Alternative Medicine, 2022 - Wiley Online Library
… Therefore, the measures to treat hepatitis B virus infection include antiviral therapy, which
is considered to be the current strategy of choice. The main antiviral drugs are nucleotide …

Cytokine, genotype, and viral load profile in the acute and chronic hepatitis B

CRA Ribeiro, KG Martinelli, VM de Mello… - Viral …, 2020 - liebertpub.com
… and chronic hepatitis B infections. In this study, a comparison of the production of IL-35, IL-6,
IL-17A, and IFN-γ between acute and chronic infection … in individuals infected with HBV in …