[HTML][HTML] Effect of Oxaliplatin-Loaded Poly (d,l-Lactide-co-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug …
AL C. de SL Oliveira, RF Araújo Júnior… - Pharmaceutics, 2020 - mdpi.com
Apoptosis signaling pathways, drug resistance, and metastasis are important targets to
develop new cancer treatments. We developed cholesterol-coated Poly (d, l-Lactide-co-
Glycolic Acid)(PLGA) nanoparticles for effective encapsulation and delivery of retinoic acid
and oxaliplatin to analyze their antitumor activity in colorectal cancer. The cell viability and
proliferation of tumoral cells lines (CT-26 and SW-480) decreased when compared to control
in vitro after treatment with the nanoparticles. In addition, apoptosis of CT-26 cells increased …
develop new cancer treatments. We developed cholesterol-coated Poly (d, l-Lactide-co-
Glycolic Acid)(PLGA) nanoparticles for effective encapsulation and delivery of retinoic acid
and oxaliplatin to analyze their antitumor activity in colorectal cancer. The cell viability and
proliferation of tumoral cells lines (CT-26 and SW-480) decreased when compared to control
in vitro after treatment with the nanoparticles. In addition, apoptosis of CT-26 cells increased …
[PDF][PDF] Effect of Oxaliplatin-Loaded Poly (d, L-Lactide-co-Glycolic Acid)(PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug …
ABC Carvalho, T Schomann, F Tamburini… - … of nanocarriers to … - repositorio.ufrn.br
Apoptosis signaling pathways, drug resistance, and metastasis are important targets to
develop new cancer treatments. We developed cholesterol-coated Poly (d, l-Lactide-co-
Glycolic Acid)(PLGA) nanoparticles for effective encapsulation and delivery of retinoic acid
and oxaliplatin to analyze their antitumor activity in colorectal cancer. The cell viability and
proliferation of tumoral cells lines (CT-26 and SW-480) decreased when compared to control
in vitro after treatment with the nanoparticles. In addition, apoptosis of CT-26 cells increased …
develop new cancer treatments. We developed cholesterol-coated Poly (d, l-Lactide-co-
Glycolic Acid)(PLGA) nanoparticles for effective encapsulation and delivery of retinoic acid
and oxaliplatin to analyze their antitumor activity in colorectal cancer. The cell viability and
proliferation of tumoral cells lines (CT-26 and SW-480) decreased when compared to control
in vitro after treatment with the nanoparticles. In addition, apoptosis of CT-26 cells increased …
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