A novel preclinical model of migraine: systemic monosodium glutamate administration

TV Benbow - 2022 - open.library.ubc.ca
… that systemic administration of MSG produces behavioural signs of headache, nausea and
craniofacial tendernessMigraine is a disabling brain disorder that affects 16% of the world’s …

Systemic administration of monosodium glutamate induces sexually dimorphic headache-and nausea-like behaviours in rats

T Benbow, MR Ekbatan, GHY Wang, F Teja… - Pain, 2022 - journals.lww.com
… , nausea, and changes in craniofacial sensitivity in rats. The … of headache and nausea using
systemic administration of MSG… the effect of MSG with GTN, which induces headaches in …

Unraveling the MSG-Headache Controversy: an Updated Literature Review

E Ahdoot, F Cohen - Current Pain and Headache Reports, 2024 - Springer
… , Monosodium glutamate (commonly referred to as MSG) has … of its relation as not just a
headache trigger, but a cause of … of MSG, as well as the studies assessing the effects of MSG

[HTML][HTML] Peripheral N-methyl-d-aspartate receptor activation contributes to monosodium glutamate-induced headache but not nausea behaviours in rats

T Benbow, F Teja, A Sheikhi, FG Exposto… - Scientific Reports, 2022 - nature.com
… in reports of headache, craniofacial sensitivity and nausea in … which uses systemic
administration of MSG to induce headache-… We also investigated the effects of MTC and OND on …

[HTML][HTML] Targeting glutamate neurotoxicity through dietary manipulation: Potential treatment for migraine

F Martami, KF Holton - Nutrients, 2023 - mdpi.com
monosodium glutamate (MSG) neurotoxicity in the hippocampus of prepubertal rats [110].
This neuroprotective effect of … sensitivity of NMDA receptors to glutamate-mediated CSD [134]. …

Dysregulation of the peripheral glutamatergic system: A key player in migraine pathogenesis?

T Benbow, BE Cairns - Cephalalgia, 2021 - journals.sagepub.com
… of 50 mg/kg monosodium glutamate (MSG). During the 5-min … with reports headache and
craniofacial muscle sensitivity. In a … of side effects owing to their effects on central glutamate

[PDF][PDF] Monosodium Glutamate as Flavor Enhancer in Foods: Toxicity and Related Health Issues

DJ Manisha - An Overview of Toxicants - researchgate.net
… of flushing, headaches, restlessness, muscle tightness and tingling/ … In 2000, 130 MSG
sensitive volunteers participated in this study. … Effect of monosodium glutamate and aspartame on …

[HTML][HTML] Glutamate and Migraine

B Mutlu, AŞ Acar, O Erbaş - Journal of Experimental and Basic Medical …, 2021 - jebms.org
… These are heart and muscle sensitivity, high sensitivity to … Monosodium glutamate
administration caused headache in … CSD is also inhibited by systemic administration of kinurine, …

Modulation of Glutamate for Chronic Pain Management

KF Holton - Glutamate and Neuropsychiatric Disorders: Current …, 2022 - Springer
… cytokines which affect glutamate, improvement in glutamatergic and … Monosodium glutamate
(MSG) is a well-known flavor … of sensitivity to MSG as a trigger for primary headache and …

[HTML][HTML] Targeting peripheral N-Methyl-D-Aspartate Receptor (NMDAR): A novel strategy for the treatment of migraine

V Kalatharan, MAM Al-Karagholi - Journal of Clinical Medicine, 2023 - mdpi.com
… , administration of monosodium glutamate (MSG) activated … of MSG caused headaches,
craniofacial sensitivity, and … microiontophoretic application and systemic administration to …