… of response in NSCLC patients with EGFR mutations (EGFRm). … Also, high tumor uptake of
11 C-erlotinib or 18 F-afatinib was … -osimertinib and 18 F-afatinib may have led to a sink effect, …

… In this study, 10 subjects with NSCLC and assorted EGFR mutation … Normalized tracer uptake
was found to stabilize … of NSCLC and its apparent impact on [ 11 C]-erlotinib kinetics. A lack …

… tracer uptake was studied in patients exposed to 11 C-erlotinib, … lysosomal sequestration
mainly impacts the tumor uptake (Table … in advanced stage, EGFR mutated NSCLC patients. No …

… in NSCLC, assessing EGFR mutation and planning treatment … high spleen and liver uptake
leading to a sink effect with less … (A) 11 C-erlotinib showing pathologic uptake in three lymph …

… demonstrated uptake and retention in three NSCLC xenografts… uptake was observed in the
primary Del19 EGFR mutated … to osimertinib treatment than to erlotinib or afatinib treatment (…

… EGFR-TKIs (erlotinib and gefitinib) in the first-line treatment of EGFR mutation-positive
advanced NSCLC (… for the wild-type EGFR, it cannot be excluded that the uptake observed in the …

… , erlotinib and osimertinib, have revolutionized the treatment … SUVmax and EGFR mutation
status in NSCLC patients, we … Our results showed that EGFR-mutant patients had higher …

… EGFR-TKIs (gefitinib, erlotinib, and afatinib) for NSCLC … Thus, EGFR mutation status detection
during treatment is … received erlotinib therapy correlated strongly with the uptake of [11C] …

… We compared gut absorption of inhibitors of epidermal growth factor receptor (… the treatment
of adenocarcinoma of non-small cell lung cancer (NSCLC) with activating EGFR mutations. …

… (EGFR) tyrosine kinase inhibitors (TKI), such as Erlotinib, have … in the treatment of non-small
cell lung cancer (NSCLC) … in vitro antitumor effect and remarkable tumour uptake of Bev + Erl…