Dysregulation along the gut microbiota-immune system axis after oral exposure to titanium dioxide nanoparticles: A possible environmental factor promoting obesity …

B Lamas, L Evariste, E Houdeau - Environmental Pollution, 2023 - Elsevier
… the impacts of oral exposure to TiO 2 on the microbiota-immune … the effects of these inorganic
NPs to dysbiosis and intestinal … of the intestinal epithelium, the gut-associated lymphoid …

Long-term exposure to titanium dioxide nanoparticles promotes diet-induced obesity through exacerbating intestinal mucus layer damage and microbiota dysbiosis

X Zhu, L Zhao, Z Liu, Q Zhou, Y Zhu, Y Zhao, X Yang - Nano Research, 2021 - Springer
… tract and impose pressure to determine the species of gut flora to further promote HFD-induced
obesity. In this study, we investigated the disruptive effects of oral intake of TiO2-NPs (30 …

… effects of the food additives titanium dioxide and silica on the murine intestinal tract: Mechanisms related to intestinal barrier dysfunction involved by gut microbiota

J Yan, D Wang, K Li, Q Chen, W Lai, L Tian… - Environmental …, 2020 - Elsevier
oral exposure to the studied micro-/nanoparticles significantly reduced the thickness of mucus
in the small intestines of … the effects of three varieties of food-grade micro-/nanoparticles in …

Subchronic oral toxicity study of food-related titanium dioxide nanoparticles in rats involved in Ti biodistribution and gut microbiota

H Lin, J Tan, J Wang, C Xie, B Chen… - Journal of agricultural …, 2023 - ACS Publications
oral administration for 90 days. Additionally, the biodistribution of titanium (Ti) and effects of
TiO 2 NPs on gut microbiota … to elucidating the potential adverse effects of food-related TiO 2 …

Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health

B Lamas, N Martins Breyner, E Houdeau - Particle and fibre toxicology, 2020 - Springer
… NPs, titanium dioxide (TiO 2 ), silver (Ag) and silicon dioxide (… as food supplements, such
as zinc oxide (ZnO), given that … gut-associated lymphoid tissue (GALT) shape the microbiota

Impact of food additive titanium dioxide on gut microbiota composition, microbiota-associated functions, and gut barrier: a systematic review of in vivo animal studies

E Rinninella, M Cintoni, P Raoul, V Mora… - International Journal of …, 2021 - mdpi.com
… of “microbiota revolution”, potential health risks of TiO 2 NPs and their impact on the intestinal
tract and the gut microbiota are increasingly being studied. Gut microbiota is composed of …

Intestinal toxicity of micro-and nano-particles of foodborne titanium dioxide in juvenile mice: Disorders of gut microbiota–host co-metabolites and intestinal barrier …

J Yan, Q Chen, L Tian, K Li, W Lai, L Bian, J Han… - Science of the Total …, 2022 - Elsevier
… barrier are very important for intestinal health. In this study, the toxic effects of foodborne
TiO 2 micro−/nanoparticles on the intestines via oral exposure were evaluated from the …

Titanium dioxide nanoparticles: revealing the mechanisms underlying hepatotoxicity and effects in the gut microbiota

Y Ma, N Yu, H Lu, J Shi, Y Zhang, Z Chen, G Jia - Archives of Toxicology, 2023 - Springer
… the gut-liver axis. This review examines the gut-liver axis to assess the effects of gut microbiota
dysbiosis on the liver to provide suggestions for assessing the gut-hepatotoxicity of TiO 2 …

Landscape of lipidomic metabolites in gut-liver axis of Sprague–Dawley rats after oral exposure to titanium dioxide nanoparticles

Z Chen, S Han, P Zheng, J Zhang, S Zhou… - Particle and Fibre …, 2022 - Springer
… of intestinal bacteria and cause osmotic stress under dark conditions [33]. Alterations of gut
microbiota … Table 1 Physicochemical properties of titanium dioxide nanoparticles (TiO 2 NPs) …

[HTML][HTML] Dietary nanoparticles alter the composition and function of the gut microbiota in mice at dose levels relevant for human exposure

L Perez, E Scarcello, S Ibouraadaten, Y Yakoub… - Food and Chemical …, 2021 - Elsevier
… We found that long-term oral exposure to dietary NPs at doses relevant for estimated
human intakes disrupts the GM composition and function. These modifications did not appear …