The effect of statin therapy on serum uric acid levels: a systematic review and meta-analysis

A Akbari, M Razmi, M Rafiee, GF Watts… - Current Medicinal …, 2024 - ingentaconnect.com
… total cholesterol, LDL, and triglycerides (P < 0.0001), but statin … total cholesterol, LDL
cholesterol, and HDL cholesterol levels [… homeostasis could also explain the SUAlowering effects

[HTML][HTML] An effect of statin on serum uric acid in patients with dyslipidemia at a tertiary care hospital

A Palikhey, A Lodh, J Shrestha, M Karki… - … and Metabolic Science, 2023 - Elsevier
… Hence, the main objective of the present study was to evaluate the effect of statins on
blood uric acid level in patients being treated for dyslipidemia at a tertiary care hospital. …

Effects of Urate‐Lowering Therapy on Risk of Hyperlipidemia in Gout by a Population‐Based Cohort Study and on In Vitro Hepatic Lipogenesis‐Related Gene …

YJ Fang, TY Wu, CL Lin, CY Su, JR Li… - Mediators of …, 2020 - Wiley Online Library
… It is characterized by the crystallization of uric acid (UA), a product … that may play important
roles in blood lipid homeostasis. … Thus, as statins and fenofibrate are expensive medications, …

Effects of rosuvastatin on serum glucose and insulin in hyperuricemic rats

D Xilifu, Z Tuerxun, B Nuermaimaiti, A Aili… - BMC Pharmacology and …, 2022 - Springer
Uric acid (UA) is a diprotic acid of the final decomposition … Statins are usually used to
decrease the serum cholesterol levels … The homeostasis model assessment of insulin resistance (…

[HTML][HTML] Effects of Xanthine Oxidase Inhibition by Febuxostat on Lipid Profiles of Patients with Hyperuricemia: Insights from Randomized PRIZE Study

Y Saito, A Tanaka, H Yoshida, H Nakashima, N Ban… - Nutrients, 2024 - mdpi.com
dyslipidemia (eg, statins) may be important in improving clinical outcomes in this patient
population [6]; however, the effects of uric acid-… between dyslipidemia and uric acid requires …

Association between baseline serum uric acid and development of LDL-C level in patients with first acute myocardial infarction

Y Chen, C Ding, L Hu, Y Ruan, K Zou, C Dai… - BMC Cardiovascular …, 2021 - Springer
… concentrations was r = 0.64 but only r = − 0.07 between the cholesterol and uric acid levels[8…
benefits from statin lipid-lowering therapy due to the uric acid-lowering effect of statins. Third…

Elevated triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio increased risk of hyperuricemia: a 4-year cohort study in China

XY Liu, QY Wu, ZH Chen, GY Yan, Y Lu, HJ Dai, Y Li… - Endocrine, 2020 - Springer
… A genome-wide association study found that hyperuricemia and genes mediating uric acid
homeostasis are significantly associated with the overweight/obese state [54]. In addition, …

Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

M Guma, B Dadpey, R Coras, TR Mikuls… - … research & therapy, 2022 - Springer
… Moreover, effects of ULT on blood triglycerides and cholesterol have been inconclusive …
in regulating FA homeostasis [38]. However, the impact of purine and uric acid metabolism is …

Bempedoic acid in the treatment of patients with dyslipidemias and statin intolerance

AV Susekov, LA Korol, GF Watts - Cardiovascular drugs and therapy, 2021 - Springer
patients with hyperlipidemia on stable therapy with a statin, … The most common AEs in the
ECT-1002 group were uric acidacid treatment group, a slight increase in mean uric acid

[HTML][HTML] Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis

X Hu, J Liu, W Li, C Wang, G Li, Y Zhou… - Nutrition, Metabolism and …, 2022 - Elsevier
Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and … of the
patients in this subsample used statins [39,40], we considered that statins use may interference …