Efficacy and safety of edoxaban compared with warfarin according to the burden of diseases in patients with atrial fibrillation: insights from the ENGAGE AF-TIMI 48 …

AM Nicolau, R Corbalan, JC Nicolau… - European Heart …, 2020 - academic.oup.com
… analysis of the ENGAGE AF-TIMI 48 trial in patients with AF, … and the relative efficacy and
safety of edoxaban vs. warfarin. Our … death, the efficacy and safety profile of edoxaban would be …

Edoxaban versus warfarin in patients with atrial fibrillation at the extremes of body weight: an analysis from the ENGAGE AF-TIMI 48 trial

G Boriani, CT Ruff, JF Kuder, M Shi… - Thrombosis and …, 2021 - thieme-connect.com
… [1] [2] [3] [4] Limited data are available on the efficacy and safety of NOACs in patients at the
… in the ENGAGE AFTIMI 48 trial the outcome of atrial fibrillation (AF) patients differed across …

[HTML][HTML] Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial

C Wilkinson, J Wu, SD Searle, O Todd, M Hall… - BMC medicine, 2020 - Springer
… on the efficacy and safety of DOAC in older people with AF … of the ENGAGE AF-TIMI 48 trial
was that edoxaban was … with warfarin, with similar efficacy in stroke and systemic embolism …

[HTML][HTML] Pharmacokinetics of Edoxaban 15 mg in Very Elderly Patients with Nonvalvular Atrial Fibrillation: A Subanalysis of the ELDERCARE-AF Study

T Yamashita, Y Igawa, M Fukuzawa… - Thrombosis and …, 2024 - thieme-connect.com
edoxaban in very elderly ELDERCARE-AF patients with those in ENGAGE AF-TIMI 48,
edoxaban 15 mg appears to be therapeutically effective for very elderly patients. This is based on …

Comparison of the efficacy and safety outcomes of edoxaban in 8040 women versus 13 065 men with atrial fibrillation in the ENGAGE AF-TIMI 48 trial

TA Zelniker, M Ardissino, F Andreotti, ML O'Donoghue… - Circulation, 2021 - Am Heart Assoc
… Female sex is an independent risk factor for stroke and systemic embolic events in patients
with atrial fibrillation. This study aimed to examine the efficacy and safety profile of edoxaban

[HTML][HTML] Low-dose edoxaban in very elderly patients with atrial fibrillation

K Okumura, M Akao, T Yoshida… - … England Journal of …, 2020 - Mass Medical Soc
… in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) phase
3 trial, 8 both once-daily doses of edoxaban (a high dose of 60 mg [or 30 mg in patients who …

[HTML][HTML] Edoxaban versus warfarin in patients with atrial fibrillation in relation to the risk of stroke: A secondary analysis of the ENGAGE AF-TIMI 48 study

JR de Groot, CT Ruff, SA Murphy, RA Hamershock… - American heart …, 2021 - Elsevier
… score for edoxaban. The trial design and data collection in ENGAGE AF-TIMI 48 precluded
… Forty percent of the patients randomized to warfarin were naïve to VKA at study enrollment, …

… -and bleeding-related hospitalization rates with edoxaban versus warfarin in patients with atrial fibrillation based on results of the ENGAGE AFTIMI 48 trial

…, ENGAGE AF-TIMI 48 Trial Investigators - … Quality and Outcomes, 2020 - Am Heart Assoc
… In this analysis of patient-level hospitalization rates from the ENGAGE AFTIMI 48 trial,
edoxaban 60/30 mg significantly reduced the overall rate of cardiovascular- or bleeding-related …

Effectiveness and safety of edoxaban in patients with atrial fibrillation: data from the Danish Nationwide Cohort

PB Nielsen, TB Larsen, F Skjøth… - European Heart …, 2021 - academic.oup.com
… the ENGAGE AF-TIMI 48 trial. Studies investigating comparative effectiveness and safety for
edoxaban in … Real-life performance of edoxaban in elderly patients with atrial fibrillation: a …

… hemorrhage in patients with atrial fibrillation receiving anticoagulation with warfarin or edoxaban: An in-depth analysis from the ENGAGE AF-TIMI 48 randomized trial

SE Nelson, RP Giugliano, EM Antman, JG Park… - Journal of Clinical …, 2021 - Elsevier
… in the setting of edoxaban vs warfarin plus pharmacodynamic … patients with AF regarding
safety of anticoagulation. Using data from ENGAGE AF-TIMI 48, we investigated ICH patients’ …