[HTML][HTML] Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients

…, H Zhang, Y Li, AB Kumar, J Failing… - Melanoma …, 2020 - journals.lww.com
One of the barriers in developing efficacious salvage … CIT combination reported in NSCLC
studies [ 12 , 18 ], we have employed the addition of cytotoxic chemotherapy to ongoing PD-1

Efficacy and safety of antiPD1/PD‐L1 in combination with chemotherapy or not as first‐line treatment for advanced non‐small cell lung cancer: a systematic review …

L Wang, Y Yang, J Yu, S Zhang, X Li, X Wu… - Thoracic …, 2022 - Wiley Online Library
… into the form of lnHR and standard error of lnHR (selnHR). As … of 185 records were reviewed
for full-text assessment after … that the combination of Pembro/Atez and Chemo are preferred …

Effectiveness of chemotherapy after antiPD1 blockade failure for relapsed and refractory Hodgkin lymphoma

B Casadei, L Argnani, A Morigi, G Lolli… - Cancer …, 2020 - Wiley Online Library
chemo-refractory HL patients treated with salvage chemotherapy after anti-PD1 blockade
failure, … CHT was combined to anti-PD1 in comparison to those in which CHT was administered …

[HTML][HTML] Efficacy of salvage therapies after failure of adjuvant anti-PD-1 monotherapy for melanoma in the Chinese population: a multi-institutional cohort study

DD Jia, Y Xu, T Li, JL Yang, Y Chen, T Li - Investigational New Drugs, 2023 - Springer
chemotherapy, 2 (66.7%) patients who were treated with adjuvant chemotherapy and
pembrolizumab combined and 3 (100… adjuvant radiotherapy and pembrolizumab combined had …

The effect of low-dose chemotherapy on the tumor microenvironment and its antitumor activity combined with anti-PD-1 antibody

F Lin, H Chen, T Jiang, J Zheng, Q Liu, B Yang… - …, 2022 - Taylor & Francis
… and low-dose 5-fluorouracil changed the TME, both failed to … Chemotherapy, radiotherapy
and targeted therapy can … antibody to improve the efficacy and safety of the combination

[HTML][HTML] Efficacy and safety of PD-1 inhibitors combined with chemotherapy as first-line therapy for advanced esophageal cancer: a systematic review and network …

ZC Li, YT Sun, MY Lai, YX Zhou, MZ Qiu - International …, 2022 - Elsevier
After rigorous screening, 5 studies involving a total of 3,163PD-1 inhibitors plus
chemotherapy combinations, tori-chemo … However, we failed to find similar results in our analysis. …

[HTML][HTML] Anti-PD-1 therapy plus chemotherapy and/or bevacizumab as second line or later treatment for patients with advanced non-small cell lung cancer

F Zhang, D Huang, T Li, S Zhang, J Wang… - Journal of …, 2020 - ncbi.nlm.nih.gov
… the efficacy of combined therapy of PD-1 inhibitor with … A total of 50 (90.9%) patients in this
study have failed after … plus beva and 75% (3/4) in anti-PD-1 plus chemo/beva. The DCR was …

Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action

Y Xue, S Gao, J Gou, T Yin, H He, Y Wang… - Expert opinion on …, 2021 - Taylor & Francis
… surgery, radiotherapy and chemotherapy [Citation4]. However… KEYNOTE-021 was first
conducted to evaluate the efficacy of … undergone systemic treatment failure. Toripalimab displayed …

[HTML][HTML] A combination of PD1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy

X Kong, P Lu, C Liu, Y Guo… - Molecular …, 2021 - spandidos-publications.com
… Tim-3 (+) PD-1 (+) TILs is a severe failure phenotype, which does not proliferate to produce
… with chemotherapy alone (93,94). Anti-PD-1 therapy enhances the efficacy of radiotherapy in …

[HTML][HTML] Anti-PD1 checkpoint inhibitor with or without chemotherapy for patients with recurrent and metastatic nasopharyngeal carcinoma

T Jin, Q Zhang, QF Jin, YH Hua, XZ Chen - Translational Oncology, 2021 - Elsevier
… NPC is highly sensitive to chemotherapy and radiotherapy. … the efficacy and safety of anti-PD1
checkpoint inhibitor plus … PFS was defined as the date of starting treatment to first failure at …