Soluble ST2: A complex and diverse role in several diseases

E Homsak, D Gruson - Clinica chimica acta, 2020 - Elsevier
… They also found a differential rise of serum sST2 level that correlates well with the severity
of asthma exacerbation. Their results revealed that soluble human ST2 in sera could be …

Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial

AJ Yousuf, S Mohammed, L Carr… - The Lancet …, 2022 - thelancet.com
… median serum soluble ST2 (sST2) concentration determined by … exacerbation rate reduction
in patients with higher serum … can request access to individual patient-level data through the …

[HTML][HTML] ST2-mediated neutrophilic airway inflammation: a therapeutic target for patients with uncontrolled asthma

QL Quoc, TBT Cao, JH Jang, YS Shin… - Allergy, Asthma & …, 2024 - ncbi.nlm.nih.gov
… were enrolled to compare serum levels of soluble ST2 (sST2) … and 105 asthmatic patients
to measure the serum levels of … and ST2 mRNA expressions were significantly increased in …

Serum levels of interleukin-33, soluble ST2 and IgE in patients with asthma: a case-control study

H Singh, A Khurana, A Kumar, R Saluja - Journal of Asthma, 2024 - Taylor & Francis
elevated IL-33 and IgE levels and decreased sST2 levels in … levels during exacerbation than
stable asthmatic patients (20)… demonstrated that asthma is associated with serum levels of IL…

[HTML][HTML] Soluble ST2 enhances IL‐33–induced neutrophilic and pro‐type 2 inflammation in the lungs

M Watanabe, K Nakamoto, T Inui, M Sada, K Chibana… - Allergy, 2022 - ncbi.nlm.nih.gov
high serum levels of sST2 predict unfavorable outcomes in patients with pneumonia 1 or
asthma, 2 … in their sputum experience more asthma exacerbation and poorer lung function than …

Soluble ST2 and all-cause mortality in patients with chronic obstructive pulmonary disease—a 10-year cohort study

MH Urban, S Stojkovic, S Demyanets… - Journal of Clinical …, 2021 - mdpi.com
concentrations of IL-33 and sST2 in the serum of patients with stable COPD (n = 59), patients
with acute exacerbation … [37] and can be deduced from high levels of decoying sST2 in our …

Diagnostic and Prognostic Values of Serum Selenoprotein P and Soluble St2 Levels in Pulmonary Embolism

N Boyracı, S Tural Onur, K Kara, F Tokgöz Akyıl… - … and Soluble St2 Levels … - papers.ssrn.com
Soluble ST2 level was first interrogated on … sST2 in serum might be associated with
Th2-mediated allergic inflammation by inducing acute exacerbation in patients with atopic asthma (25…

Serum soluble ST2 correlated with symptom severity and clinical response of sublingual immunotherapy for House dust mite‐induced allergic rhinitis patients

K Zhu, C Xia, J Chen, C Yu, T Gao, J Yan… - Mediators of …, 2021 - Wiley Online Library
… and aggravate disease activity in asthma and food allergy [17–… serum sST2 concentrations
were increased in AR patients … , resulting in exacerbation of allergic symptoms in AR patients […

[HTML][HTML] Next-Generation Therapeutic Approaches for Uncontrolled Asthma: Insights Into the Heterogeneity of Non-Type 2 Inflammation

SR Kim - Allergy, Asthma & Immunology Research, 2024 - ncbi.nlm.nih.gov
… authors demonstrated the potential of soluble ST2 (sST2) as … When asthmatic patients were
classified into sST2-high and … treatment of severe asthma with a low blood eosinophil count …

[PDF][PDF] Soluble ST2 is increased in systemic lupus erythematous and is a potential marker of lupus nephritis

A Moreau, C Nicaise, A Awada, MS Soyfoo - Clin Exp Rheumatol, 2021 - dipot.ulb.ac.be
… and IgG1 7 production in patients with sepsis and trauma. Intensive care medicine 2004; …
Elevated soluble ST2 protein levels in sera of 9 patients with asthma with an acute exacerbation