… not investigate the role of nuclear FAK in ovarian cancer or any … analyses of human cancers
have provided new insights into … better understand FAK’s role in the nucleus of cancer cells. …

… the cytoskeleton of the cell and the extra cellular matrix (ECM), the cell-ECM adhesions with
integrins at their core, play a major role in cell signalling to direct mechanotransduction, cell …

… Focal adhesion kinase (FAK) is a nonreceptor intracellular tyrosine kinase that plays an
essential role in cancer cell adhesion… activities and scaffolding functions. Overexpression of FAK …

… enhancing actin rearrangements and focal adhesion formation. Furthermore, we demonstrate
that Cdh1 loss and RHOA Y42C induce DGC via activation of focal adhesion kinase (FAK), …

… that aGPCRs play important roles in cell adhesion to the extracellular matrix and cell–cell
communication, processes that are dysregulated in cancer. Emerging evidence suggests that …

… , colon cancer and other cancers and promotes tumor progression, invasion and metastasis.
… kinase 4 proteins. CEACAM6 can activate the ERK1/2/MAPK or SRC/focal adhesion kinase/…

… We found that the protein FAK (focal adhesion kinase) is upregulated and activated in
human and mouse intrahepatic cholangiocarcinoma samples. FAK promotes intrahepatic …

… Focal adhesion kinase (FAK) may represent a new therapeutic target in KRAS mutant lung
cancer. … non-receptor tyrosine kinase that has roles in cellular adhesion, migration, and stem …

… promoted focal adhesion disassembly at rear-edge of the cell. … role in the tumorigenicity
and metastasis of gastric cancer. … Focal adhesion kinase (FAK), a nonreceptor protein tyrosine …

… kinase with key roles in the regulation of cell adhesion migration, proliferation and survival.
In cancer FAK … Focal adhesion kinase (FAK) was discovered almost three decades ago as a …