TRPV1 modulation of contextual fear memory depends on stimulus intensity and endocannabinoid signalling in the dorsal hippocampus

LP Iglesias, HB Fernandes, AS de Miranda… - …, 2023 - Elsevier
TRPV1 blocker, into the dorsal hippocampus selectively disrupted fear memory consolidation
in rats … Complementing this result, we investigated if the endocannabinoid system would be …

… of the endovanilloid receptor, TRPV1, and of the endocannabinoid enzyme, FAAH, within the nucleus accumbens shell elicits anxiolytic-like effects in male rats

TR Pardo-García, N Yusif-Rodriguez, G Yudowski… - Neuroscience …, 2020 - Elsevier
… In this study, male Sprague Dawley rats were implanted with bilateral brainTRPV1
receptors regulate anxiety-like behavior through the modulation of the endocannabinoid system

CB1-cannabinoid-, TRPV1-vanilloid-and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain …

P Medeiros, M Oliveira-Silva, SE Negrini-Ferrari… - Brain Research …, 2020 - Elsevier
… 1 receptor modulation was evaluated 21 days after chronic constriction injury (CCI) of the
sciatic nerve in male Wistar rats… the activation of the endocannabinoid system by AEA produces …

The role of endocannabinoid system and TRPV1 receptors in the antidepressant and anxiolytic effects of dipyrone in chronic unpredictable mild stress in mice

RD Topuz, MZ Cetinkaya, D Erumit, KD Aydemir… - European Journal of …, 2021 - Elsevier
… Cannabinoids have effects on many physiological processes such as pain modulation, …
Similar to our results, no changes were reported in AEA levels in the hippocampus, striatum …

Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT1A and TRPV1 receptor mechanisms

E Galaj, GH Bi, HJ Yang, ZX Xi - Neuropharmacology, 2020 - Elsevier
… blocked by AM630 (a cannabinoid CB2 receptor antagonist), … release and modulating the
mesolimbic DA system. This … and brain-stimulation reward, an effect that was blocked by a …

Differential modulation of the contextual conditioned emotional response by CB1 and TRPV1 receptors in the ventromedial prefrontal cortex: possible involvement of …

DL Uliana, LS Antero… - Journal of …, 2020 - journals.sagepub.com
cannabinoid CB1 or vanilloid TRPV1 receptors in the ventromedial prefrontal cortex of rats
… emotional response evoked by a CB1 antagonist or by a TRPV1 agonist in this brain region. …

Cellular distribution of cannabinoid‐related receptors TRPV1, PPAR‐gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia

G Galiazzo, M De Silva, F Giancola… - Equine Veterinary …, 2022 - Wiley Online Library
… control pathway, namely the endocannabinoid system (ECS). … four cannabinoid-related
receptors, specifically modulated … residues 824-838 of rat TRPV1. The homology between the …

TRPV1 channels in nitric oxide-mediated signalling: Insight on excitatory transmission in rat CA1 pyramidal neurons

G Gambino, D Gallo, A Covelo, G Ferraro… - Free Radical Biology …, 2022 - Elsevier
… of presynaptic type 1 cannabinoid (CB1) receptors [27,28]. … of TRPV1 in nitric oxide-mediated
modulation of hippocampal … neurons of CA1 area of hippocampus, exploring the possible …

… absence of the transient receptor potential vanilloid 1 directly impacts on the expression and localization of the endocannabinoid system in the mouse hippocampus

J Egaña-Huguet, I Bonilla-Del Rio… - Frontiers in …, 2021 - frontiersin.org
… tested whether the absence of TRPV1 affects the endocannabinoid system. The results …
TRPV1 show that the expression and localization of components of the endocannabinoid system, …

TRPV1 blockers as potential new treatments for psychiatric disorders

LP Iglesias, DC Aguiar, FA Moreira - Behavioural Pharmacology, 2022 - journals.lww.com
… expression and function in brain regions modulating anxiety, mood … of TRPV1 and its relation
with the endocannabinoid system; … Finally, spontaneous hypertensive rats, which have also …