Advancement of cell-penetrating peptides in combating triple-negative breast cancer

M Fatima, MAS Abourehab, G Aggarwal, GK Jain… - Drug Discovery …, 2022 - Elsevier
Nanotechnology provides delivery systems with distinct … PEG) is conjugated with drugs or
antibody–drug conjugates, PDCs offer … a drug or siRNA into the cell via endocytosis. The GALA …

Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles

E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
… modifiable properties, polymeric nanoparticles (NPs) have … also be used to measure cell
penetrating peptide (CPP)-mediated … For example, conjugation of transferrin onto PLGA NPs is …

A review of Cell-penetrating peptide mediated drug delivery to the brain

ZT Tisha - 2023 - dspace.bracu.ac.bd
… mechanism moved from endocytosis to direct transport. Similar results … Cell penetrating
peptide conjugated liposomes as … nanoparticles by modification with cell-penetrating peptides. …

Advances in exosome-based drug delivery and tumor targeting: from tissue distribution to intracellular fate

J Shao, J Zaro, Y Shen - International journal of nanomedicine, 2020 - Taylor & Francis
… 103 or with conjugation with superparamagnetic nanoparticles (… by several means, including
endocytosis, phagocytosis, and … with cell-penetrating peptides (eg, arginine-rich peptide) to …

Cell penetrating peptides: A versatile vector for co-delivery of drug and genes in cancer

MM Khan, N Filipczak, VP Torchilin - Journal of controlled release, 2021 - Elsevier
Cell penetrating peptides can be conjugated with various drugs … cross the cell membrane
through endocytosis and leads to … Hyaluronic acid-Cell penetrating peptide nanoparticle siRNA …

Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells

O Tietz, F Cortezon-Tamarit, R Chalk, S Able… - Nature Chemistry, 2022 - nature.com
… However, endocytic entrapment is recognized as a … of the conjugates during the first 15 min
after their addition to HeLa … for its potential to transport biomacromolecular cargos into cells. …

Liposome Nanoparticle Conjugation and Cell Penetrating Peptide Sequences (CPPs) Enhance the Cellular Delivery of the Tau Aggregation Inhibitor RI-AG03

N Reich, D Allsop, E Parkin, N Dawson - 2023 - preprints.org
… Here, we examine the cellular uptake and intracellular trafficking of RI-AG03 when the peptide
Endocytosis of unconjugated and peptide-conjugated BODIPY-liposomes was evaluated …

Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles

M Souri, M Soltani, FM Kashkooli… - Journal of Controlled …, 2022 - Elsevier
… (such as transcellular channels and endocytosis/transcytosis)… future perspectives of nanocarrier
delivery systems are discussed. … of nanoparticles, the transport of nanoparticles can be …

[HTML][HTML] Membrane trafficking and subcellular drug targeting pathways

A Kumar, A Ahmad, A Vyawahare… - Frontiers in pharmacology, 2020 - frontiersin.org
… The endocytic trafficking of GPCR is a result of studies related … Therefore, nanoparticles
conjugated with dual peptides eg … as RGD peptide systems, cell penetrating TAT peptides etc. …

NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation

G Carreras-Badosa, J Maslovskaja, K Periyasamy… - Biomaterials, 2020 - Elsevier
… The concentration of conjugate was calculated based on the … We used TEM to visualize
whether the nanoparticles were … of miRNA along endocytic pathway trafficking, we observed a …