Bio-membrane internalization mechanisms of arginine-rich cell-penetrating peptides in various species
BR Liu, SH Chiou, YW Huang, HJ Lee - Membranes, 2022 - mdpi.com
… the early stage of intracellular trafficking, … cellular entry routes for either cell-penetrating
peptides (CPPs) alone or CPP/cargo complexes. Direct membrane translocation and endocytosis …
peptides (CPPs) alone or CPP/cargo complexes. Direct membrane translocation and endocytosis …
Cell-penetrating peptides delivering siRNAs: an overview
… most promising use for CPPs in future clinical applications. … used to conjugate the cargo
and the carrier: peptides linked … The complexes were able to enter the cells via endocytic …
and the carrier: peptides linked … The complexes were able to enter the cells via endocytic …
[HTML][HTML] Covalent conjugation and non-covalent complexation strategies for intracellular delivery of proteins using cell-penetrating peptides
Y Behzadipour, S Hemmati - Biomedicine & Pharmacotherapy, 2024 - Elsevier
… pH, the endocytic vesicles have varying fates after trafficking … CPP-conjugates are delivered
intracellularly by endocytosis and … -protein conjugation but are promising for future research. …
intracellularly by endocytosis and … -protein conjugation but are promising for future research. …
Drug conjugation induced modulation of structural and membrane interaction features of cationic cell-permeable peptides
… include the protection of the bacterial cell from the environment, transport of solutes and
proteins, … ; furthermore, an important difference in the intracellular localization was also revealed, …
proteins, … ; furthermore, an important difference in the intracellular localization was also revealed, …
Status update in the use of cell-penetrating peptides for the delivery of macromolecular therapeutics
K Kurrikoff, B Vunk, Ü Langel - Expert Opinion on Biological …, 2021 - Taylor & Francis
… delivery of resveratrol–CPP conjugate and demonstrated drug transport into the nasal epithelium
… This shows that intracellular virus trafficking is a vulnerability that can be harnessed in …
… This shows that intracellular virus trafficking is a vulnerability that can be harnessed in …
Design of polymeric carriers for intracellular peptide delivery in oncology applications
… With regard to ACPs with intracellular targets, while the conjugation/fusion of these …
into cells through energy-mediated, vesicular transport. Endocytosis of peptides or peptide-loaded …
into cells through energy-mediated, vesicular transport. Endocytosis of peptides or peptide-loaded …
Cell-penetrating peptides (CPPs) and peptide-drug conjugate systems (PDCs): site-specific delivery of bioactive (s) for effective breast cancer therapy
L Gautam, P Shrivastava, SP Vyas - Targeted Nanomedicine for Breast …, 2022 - Elsevier
… The mechanism of the transport/internalization is endocytosis. … application of these peptides
is in the intracellular delivery of … Because of their future applications in cancer, it is assumed …
is in the intracellular delivery of … Because of their future applications in cancer, it is assumed …
… Escape 10.1. 1 Introduction Cell-penetrating peptides (CPPs) are peptides that can enter the cytoplasm of cells. Through direct conjugation or coincubation methods …
E Escape, AR Prater, JP Pellois - Cell-Penetrating Peptides …, 2022 - books.google.com
… to contain more extracellular material. From here, vesicles … retrograde transport or continue
through the endocytic pathway … reduce the endocytic uptake of Tat and Tat-conjugates [27, 28]…
through the endocytic pathway … reduce the endocytic uptake of Tat and Tat-conjugates [27, 28]…
Cell-penetrating peptides and transportan
Ü Langel - Pharmaceutics, 2021 - mdpi.com
… CPPs have been extensively employed to transport cargo … The conjugate was designed to
be reduced by intracellular … , but when conjugated to cargoes, both by endocytosis and direct …
be reduced by intracellular … , but when conjugated to cargoes, both by endocytosis and direct …
Discovery of endosomalytic cell-penetrating peptides based on bacterial membrane-targeting sequences
C An, S Wei, Y Dao, X Wang, W Dong, X You, C Tian… - Bioorganic …, 2023 - Elsevier
… , particularly the endocytic delivery of biomacromolecules. … of the cell membrane is the
control of material transportation, … -l/d-EcMTS conjugates increased over 100 % as the peptide …
control of material transportation, … -l/d-EcMTS conjugates increased over 100 % as the peptide …