[HTML][HTML] Peptide-based delivery of therapeutics in cancer treatment
T Samec, J Boulos, S Gilmore, A Hazelton… - Materials Today Bio, 2022 - Elsevier
… cell receptors that bind to proteins in the extracellular matrix [74]. … -conjugated nanoparticles
and cell penetrating peptide … delivery, pinocytosis and clathrin-mediated endocytosis are …
and cell penetrating peptide … delivery, pinocytosis and clathrin-mediated endocytosis are …
[HTML][HTML] Recent advances of studies on cell-penetrating peptides based on molecular dynamics simulations
J Ouyang, Y Sheng, W Wang - Cells, 2022 - mdpi.com
… With the ability to transport cargo molecules across cell … and R8 peptides enter HeLa cells
switches from endocytosis to … The conjugation of peptides offers a possible pathway for the …
switches from endocytosis to … The conjugation of peptides offers a possible pathway for the …
Transcytosis mechanisms of cell‐penetrating peptides: Cation‐independent CC12 and cationic penetratin
M Zhu, H Liu, W Cao, Y Fang, Z Chen… - Journal of Peptide …, 2022 - Wiley Online Library
… CPPs and their conjugates could penetrate cell membranes via … that endocytosis is the
main pathway for the transport of … penetrate the membrane partially through the endocytic …
main pathway for the transport of … penetrate the membrane partially through the endocytic …
[HTML][HTML] State of art: Cell penetration and cell-penetrating peptides and proteins
S Reissmann - Health Educ. Public Health, 2021 - healtheducationandpublichealth …
… which can penetrate live cells and can transport cargoes and … internalization of peptides and
proteins conjugated to fluorescent … Future research should be focused on such diseases for …
proteins conjugated to fluorescent … Future research should be focused on such diseases for …
Endosomal escape cell-penetrating peptides significantly enhance pharmacological effectiveness and CNS activity of systemically administered antisense …
… However, both conjugates showed a punctate intracellular … cells which contributes to the
unfavourable trafficking across the … cell surface interaction and preventing the endocytosis of the …
unfavourable trafficking across the … cell surface interaction and preventing the endocytosis of the …
Cell-permeable peptide-based delivery vehicles useful for subcellular targeting and beyond
K Stillger, I Neundorf - Cellular Signalling, 2023 - Elsevier
… Based on distinct molecules involved endocytosis is differentiated … chimeric cell-permeable
peptides were used to transport specific … Finally, we synthesized peptide–drug conjugates by …
peptides were used to transport specific … Finally, we synthesized peptide–drug conjugates by …
Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles
E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
… it can also be used to measure cell penetrating peptide (CPP)-… Then, the other half of the GFP
was conjugated to the cargo-… elucidate endocytosis and intracellular trafficking mechanisms…
was conjugated to the cargo-… elucidate endocytosis and intracellular trafficking mechanisms…
[HTML][HTML] Examining the cellular transport pathway of fusogenic quantum dots conjugated with Tat peptide
J Dai, J Wang, X Yang, Z Xu, G Ruan - Frontiers in Bioengineering …, 2022 - frontiersin.org
… of intracellular-targeted delivery of quantum dots into the cell … We then investigated which
of the known endocytosis … for >50 cells), indicating that SDots-Tat’s fate in the cell nucleus is …
of the known endocytosis … for >50 cells), indicating that SDots-Tat’s fate in the cell nucleus is …
[HTML][HTML] Cell-penetrating peptides in protein mimicry and cancer therapeutics
… Finally, antibody/antigen CPP conjugates and their potential … of CPP-aided drug delivery for
future cancer therapies and … able to use both direct and endocytic routes of internalization. It …
future cancer therapies and … able to use both direct and endocytic routes of internalization. It …
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity
CM Backlund, RL Holden… - Proceedings of the …, 2022 - National Acad Sciences
… + T cell priming through improved lymph trafficking/lymph … Based on these findings, we
focused on conjugates of pAntp … antigen uptake into DCs via endocytosis in vitro, we suspected …
focused on conjugates of pAntp … antigen uptake into DCs via endocytosis in vitro, we suspected …