… matrix stiffness or integrin-modulating antibodies, … endothelial cells, the pro-inflammatory
cytokine TNF-α regulates internalization of α5β1, leading to reduced presence of α5β1 integrins …

… expressed in most cells including pericytes, endothelial cells, … integrin α5β1 contributed to
tumor cell proliferation in vitro … of α5β1 integrin have been applied by modulating the integrin …

… stress directly modulate endothelial gene expression and … compared to static control in vitro,
whereas atheroprone oscillatory … endothelial α5β1 by increasing calcium influx through the …

… Upon inflammation, β1 integrins translocate to α5β1-integrin … -1 on endothelial cells for
binding to the LFA-1 integrin on … even though integrin blockade may significantly modulate the …

… barrier, which is constituted by both endothelial cells and … which suggested expression of
integrins α6β1, α5β1 and αvβ1, … a role for endothelial laminins 511 and 411 in modulating the …

… the pro-inflammatory effects of the cytokine but the specific … the endothelial cell layer removed
by passing a pin through … blood vessels to TNFα in vitro. We previously demonstrated that …

… in quiescent vessels in vivo. Following injury, fibronectin and integrin α5β1 expression is …
by vascular cells, including endothelial cells, and its expression levels are upregulated …

… its effects on the expression of the master inflammatory cytokine, IL-1 … -5 expression in
endothelial cells, while also regulating … that modulating (activating or inhibiting) α5β1 integrin after …

… modulating their cytokine production and gene expression of … increase in integrin α5β1
expression in endothelial cells 54 . … mechanism to modulate hMSC adhesion in vivo, to prevent …

… responses in human endothelial cells, characterized by NF-… Active PDE4 is known to modulate
inflammation by degrading … been established by both in vitro and in vivo studies (38, 65, …