Vascular endothelial glycocalyx damage and potential targeted therapy in COVID-19

D Zha, M Fu, Y Qian - Cells, 2022 - mdpi.com
… many reports of glycocalyx injury in COVID… damage in severe COVID-19. In addition, the
mechanisms of COVID-19-induced endothelial glycocalyx damage and the potential therapeutic

The endothelial glycocalyx: a possible therapeutic target in cardiovascular disorders

A Milusev, R Rieben, N Sorvillo - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
… of glycocalyx components in regulating inflammatory responses and discuss possible
therapeutic … Disturbed or reduced flow profiles are known to damage the endothelial glycocalyx

Endothelial glycocalyx in traumatic brain injury associated coagulopathy: potential mechanisms and impact

Z Zou, L Li, N Schäfer, Q Huang, M Maegele… - Journal of …, 2021 - Springer
… abnormalities, is potentially avoidable and profoundly affects the therapeutic process and …
The endothelial glycocalyx, the first line of defense against endothelial injury, plays a vital role …

Targeting endothelial dysfunction in acute critical illness to reduce organ failure

NP Juffermans, CE van den Brom… - Anesthesia & …, 2020 - journals.lww.com
… effects on the endothelial glycocalyx, aggravating endothelial … ensure organ perfusion through
an injured microvasculature. … a potential therapeutic target to protect endothelial integrity. …

The endothelial glycocalyx as a target of ischemia and reperfusion injury in kidney transplantation—where have we gone so far?

A Duni, V Liakopoulos, V Koutlas, C Pappas… - International Journal of …, 2021 - mdpi.com
… of markers of endothelial glycocalyx damage either in the … endothelial glycocalyx in the
setting of kidney transplantation, which would be crucial for exploring potential therapeutic targets

[HTML][HTML] Targeting repair of the vascular endothelium and glycocalyx after traumatic injury with plasma and platelet resuscitation

M Barry, S Pati - Matrix biology plus, 2022 - Elsevier
… (i) the pathophysiology of endothelial glycocalyx and vascular … Altogether these studies
suggest that albumin has therapeutic benefits … shedding in patients and whether this is a potential

Endothelial glycocalyx

J Jedlicka, BF Becker, D Chappell - Critical care clinics, 2020 - criticalcare.theclinics.com
Endothelial glycocalyx and trauma A frequently occurring facet of trauma is a concomitant
… microcirculation might offer an improved diagnostic target and help in therapeutic decisions. …

Vascular endothelial injury exacerbates coronavirus disease 2019: The role of endothelial glycocalyx protection

H Okada, S Yoshida, A Hara, S Ogura… - …, 2021 - Wiley Online Library
prospective review, we summarize the importance of the glycocalyx and its potential as a
therapeutic target … Here, we review the possible roles of the endothelial glycocalyx in COVID-19 …

Endothelial glycocalyx degradation in critical illness and injury

EK Patterson, G Cepinskas, DD Fraser - Frontiers in Medicine, 2022 - frontiersin.org
… in these patients, raising the possibility that the glycocalyx may be a potential steroid target
(103). … compounds available for human use which may provide therapeutic benefit (111, 112). …

[HTML][HTML] Endothelial glycocalyx damage as a systemic inflammatory microvascular endotheliopathy in COVID-19

M Yamaoka-Tojo - Biomedical journal, 2020 - Elsevier
endothelial glycocalyx. In the current review, we propose new concepts and therapeutic goals
for COVID-19-related vascular endothelialendothelial glycocalyx has the potential to not …