[HTML][HTML] The critical role of signal transducers and activators of transcription-3 in the proliferation of vascular smooth muscle cells
S Li, C Liu - Journal of Holistic Integrative Pharmacy, 2023 - Elsevier
… in the transition between driving contraction and synthetic phenotypes. The myocardin-SRF
complex directly activates a variety of contracting smooth muscle genes by interacting with …
complex directly activates a variety of contracting smooth muscle genes by interacting with …
Activation of Nrf2 in Mice Causes Early Microvascular Cyclooxygenase-Dependent Oxidative Stress and Enhanced Contractility
… in vascular smooth muscle … endothelin type A receptor and thromboxane A 2 synthase,
and increased the excretion of 8-isoprostane F 2α and the microarteriolar ROS and contractions …
and increased the excretion of 8-isoprostane F 2α and the microarteriolar ROS and contractions …
Molecular mechanisms and therapeutic perspectives of peroxisome proliferator‐activated receptor α agonists in cardiovascular health and disease
… Phenotypic switch and inflammation of vascular smooth muscle cells (… pretreatment reduces
endothelin-1-induced cardiomyocyte … to uncover the comprehensive cross talk between the …
endothelin-1-induced cardiomyocyte … to uncover the comprehensive cross talk between the …
Role of Vasoactive Hormone-Induced Signal Transduction in Cardiac Hypertrophy and Heart Failure
NS Dhalla, KO Mota, V Elimban, AK Shah… - Cells, 2024 - mdpi.com
… Endothelin-1 has been shown to produce smooth muscle contraction by activating ET A
receptors… but there may also occur cross talk between their receptor mechanisms. For example, …
receptors… but there may also occur cross talk between their receptor mechanisms. For example, …
Vascular actions of peripheral CGRP in migraine-like photophobia in mice
BN Mason, AS Wattiez, LK Balcziak, A Kuburas… - …, 2020 - journals.sagepub.com
… of endothelin A/B receptors on smooth muscle cells (42). Co-administration of endothelin-1
(… CGRP (8-37) fully attenuates endothelin-1-induced tactile allodynia at the later stages (86). …
(… CGRP (8-37) fully attenuates endothelin-1-induced tactile allodynia at the later stages (86). …
[HTML][HTML] Oxidative stress: a unifying paradigm in hypertension
… In vascular smooth muscle cells, we demonstrated that H 2 O 2 induces posttranslational
modification of ERK1/2 and p38MAPK through tyrosine kinase–dependent, protein kinase C (…
modification of ERK1/2 and p38MAPK through tyrosine kinase–dependent, protein kinase C (…
Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin
RN Muhammad, N Sallam, HS El-Abhar - Scientific reports, 2020 - nature.com
… correlates with suppressing the gene expression of endothelin (ET)-1 and prevents the …
(EC) injury, as well as contraction and proliferation of vascular smooth muscle cell (VSMC) 27 . In …
(EC) injury, as well as contraction and proliferation of vascular smooth muscle cell (VSMC) 27 . In …
Role of mitochondrial dynamics and mitophagy of vascular smooth muscle cell proliferation and migration in progression of atherosclerosis
… On the other hand, endothelin-1 increases mitochondrial fission in VSMCs, and
endothelin-1-induced mitochondrial fission has been shown to be associated with vasoconstriction (…
endothelin-1-induced mitochondrial fission has been shown to be associated with vasoconstriction (…
Calcineurin Is a Universal Regulator of Vessel Function—Focus on Vascular Smooth Muscle Cells
A Nolze, S Matern, C Grossmann - Cells, 2023 - mdpi.com
… in regulating the contraction ability of renal vascular smooth muscle cells and consequently
… They expand these findings to other G q11 -coupled receptor agonists like angII, endothelin-…
… They expand these findings to other G q11 -coupled receptor agonists like angII, endothelin-…
Cerebrovascular effects of endothelin-1 investigated using high-resolution magnetic resonance imaging in healthy volunteers
… ET A receptors are mainly expressed on vascular smooth muscle cells and causes
vasoconstriction when activated, while ET B receptors … ET A receptor mediated contraction of …
vasoconstriction when activated, while ET B receptors … ET A receptor mediated contraction of …