Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension

YX Wang, J Reyes-García, A Di Mise… - Journal of General …, 2022 - rupress.org
… the contraction of smooth muscle cells (SMCs) of the pulmonary vasculature. Cell contraction
… types of vasodilators, including endothelin receptor antagonists, phosphodiesterase type 5 (…

Endolysosomal Ca2+ signaling in cardiovascular health and disease

S Negri, P Faris, F Moccia - International review of cell and molecular …, 2021 - Elsevier
contraction in cardiomyocytes and vascular smooth muscle cells (VSMCs), and
angiogenesis in vascular endothelial cells and endothelial colony forming cells. The sarco/endoplasmic …

[图书][B] Oxidative Stress Theory of Hypertension

R Rodrigo - 2021 - books.google.com
… to note that myofibrils contraction will occur whenever ROS increases within the vascular
smooth muscle cells, including the … Endothelin-1 limits vascular smooth muscle beta-adrenergic …

Endothelium-derived factors

Y Gao - Biology of Vascular Smooth Muscle: Vasoconstriction …, 2022 - Springer
… Vascular endothelium is composed of mainly a monolayer of endothelial cells (ECs) and
located between circulating blood and vascular smooth muscle cells (VSMCs) and the wall of …

[PDF][PDF] Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes

J Afzal, Y Liu, W Du, Y Suhail, P Zong, J Feng, V Ajeti… - Cell reports, 2022 - cell.com
Endothelin-1-induced pathological hypertrophy is mitigated on CMM, highlighting the role
of a native cardiac microenvironment in withstanding hypertrophy progression. CMM is a …

Targeting G protein‐coupled receptors for heart failure treatment

BS Thai, LY Chia, ATN Nguyen, C Qin… - British Journal of …, 2023 - Wiley Online Library
… Stimulation of adenosine A2B receptor inhibits endothelin-1induced cardiac fibroblast
proliferation and α-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling …

High Na+ Salt Diet and Remodeling of Vascular Smooth Muscle and Endothelial Cells

G Bkaily, Y Simon, A Jazzar, H Najibeddine… - Biomedicines, 2021 - mdpi.com
… elastic fibers and particularly contractile vascular smooth muscle cells (VSMCs), … smooth
muscle markers, such as cytoskeletal and contractile proteins, which include smooth muscle

Endothelins in inflammation

GA Rae, MGMO Henriques - … and antiinflammatory peptides, 2020 - taylorfrancis.com
… dependent dilation, or limit edema via direct contraction of arteriolar smooth muscle. …
Endothelin-1-induced myocardial ischaemia and oedema in the rat: involvement of the ET A receptor

Adipose tissue paracrine-, autocrine-, and matrix-dependent signaling during the development and progression of obesity

EK Johnston, RD Abbott - Cells, 2023 - mdpi.com
… Further, obese adipose tissue has an increased secretion of VEGF that results in vascular
smooth muscle proliferation, which contributes to vascular dysfunction [98]. However, this …

Effect of ghrelin receptor ligands on proliferation of prostate stromal cells and on smooth muscle contraction in the human prostate

X Wang - 2020 - edoc.ub.uni-muenchen.de
… Using an animal model, Mladenov et al. suggested that ghrelin increased the tension of
endothelin-1 induced contraction in pig femoral arteries [256]. According to previous studies, in …