… Objective: This study aimed to evaluate the activity of xanthine oxidase activity and study the
… reactive oxygen species in the failing heart (13). Xanthine oxidase also plays an important …

… enhanced in HF due to increased activity of certain enzymes, including NADPH oxidase (NOX),
xanthine oxidase (… These functions were mediated by inhibiting the increased expression …

… activity in the liver was similar between UCMS and control mice. This increased expression
… diseases including heart failure, pulmonary hypertension, sickle cell disease, and diabetes. …

… reduced XO activity in vivo and directly decreased XO mRNA expression and improved the
… density in an animal model of hypertensive diastolic heart failure [29]. In concordance with …

… This literature review investigates the action of xanthine oxidase as a component of the
biomolecular pathway against severe acute respiratory syndrome-related coronavirus-2, the …

… most studied effector of XOR expression/activity is hypoxia49,… significant elevation of XOR
expression, activity, export from … levels observed in congestive heart failure patients50. Parks …

… , increased expression of adhesion molecules, increased release of chemokines and cytokines
[22, 23]. Reduced synthesis or increased … stress by-passing xanthine oxidase. However, …

… role for increased XO activity and … or heart failure [64]. Serum levels of uric acid are
extremely predictive of mortality in subjects suffering from coronary artery disease, heart failure or …

… The xanthine oxidase (XO) inhibitory ability is an important way to evaluate the anti-… The
aim of this study was to investigate the structure-activity relationship, potential mechanism and …

… We conducted a subanalysis to compare the long-term effects of febuxostat on … term
study to examine the effect of febuxostat on cardiovascular outcomes related to increased …