[PDF][PDF] Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors

DA Sabbah, R Hajjo, K Sweidan - Current topics in medicinal …, 2020 - researchgate.net
… MAbs enhance the anticancer activity of chemotherapeutic agents such as cisplatin,
doxorubicin, irinotecan, paclitaxel, and topotecan [136-139]. Also, it was noticed that cetuximab …

Imidazoles as potential anticancer agents: an update on recent studies

P Sharma, C LaRosa, J Antwi, R Govindarajan… - Molecules, 2021 - mdpi.com
Epidermal Growth Factor Receptor (EGFR) Inhibitors The epidermal growth factor receptor
(EGFR) is a receptor … role in the physiology of epithelial cells by regulating several cellular …

[HTML][HTML] Implementing anti-epidermal growth factor receptor (EGFR) therapy in metastatic colorectal cancer: challenges and future perspectives

E Martinelli, D Ciardiello, G Martini, T Troiani… - Annals of …, 2020 - Elsevier
Epidermal growth factor receptor (EGFR) inhibitors are valuable therapeutics in metastatic
colorectal cancer (mCRC). Anti-EGFR monoclonal antibodies (MoAbs), such as cetuximab or …

Potentiating therapeutic effects of epidermal growth factor receptor inhibition in triple-negative breast cancer

KS You, YW Yi, J Cho, JS Park, YS Seong - Pharmaceuticals, 2021 - mdpi.com
epidermal growth factor receptor (EGFR) family (also known as the human epidermal growth
factor receptor … (ERBB) family) belongs to the receptor tyrosine kinase (RTK) superfamily, …

Dermatologic adverse events associated with selective fibroblast growth factor receptor inhibitors: overview, prevention, and management guidelines

ME Lacouture, V Sibaud, MJ Anadkat… - The …, 2021 - academic.oup.com
… from that seen with traditional chemotherapeutic agents. PPES with cytotoxic agents such as
… With VEGFR/platelet‐derived growth factor receptor multikinase inhibitors, painful blisters …

Systemic therapy for advanced human epidermal growth factor receptor 2–positive breast cancer: ASCO guideline update

SH Giordano, MAB Franzoi, S Temin… - Journal of Clinical …, 2022 - ingentaconnect.com
… The purpose of this guideline update is to provide oncologists, … patients with human epidermal
growth factor receptor 2 (HER2)… updated the guidelines in 2018.The goal of this guideline …

Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

Y Liu, Y Li, Y Wang, C Lin, D Zhang, J Chen… - Journal of Hematology & …, 2022 - Springer
… the combination of other RTK inhibitors and VEGFR inhibitors exerted a favorable clinical …
of the dual epidermal growth factor receptor (EGFR) inhibitor cetuximab and VEGFR inhibitor

Human epidermal growth factor receptor 2 (HER2) in advanced gastric cancer: current knowledge and future perspectives

J Palle, A Rochand, S Pernot, C Gallois, J Taïeb… - Drugs, 2020 - Springer
… The discovery of human epidermal growth factor receptor 2 (HER2) overexpression in 15–20…
new therapeutic targets and to develop new antitumor agents to improve patient outcomes. …

[HTML][HTML] Efficacy and safety of epidermal growth factor receptor (EGFR) inhibitors plus antiangiogenic agents as first-line treatments for patients with advanced EGFR …

F Chen, N Chen, Y Yu, J Cui - Frontiers in Oncology, 2020 - frontiersin.org
… to the vascular endothelial growth factor receptor (VEGFR) (11). … Epidermal growth factor
receptor and VEGF share a common … phase III RCTs, we will update the pooled results. Overall …

Current shreds of evidence on the anticancer role of EGCG in triple negative breast cancer: an update of the current state of knowledge

S Bimonte, M Cascella, A Barbieri, C Arra… - Infectious agents and …, 2020 - Springer
… as adjuvants to chemotherapeutic drugs in TNBC cells [6, 7]. … cancer cell growth by enhancing
the chemotherapeutic-… the nuclear factor-κB (NF- κβ), the epidermal growth factor receptor (…