[HTML][HTML] Epigenetic mechanisms in gastric cancer: potential new therapeutic opportunities

M Canale, A Casadei-Gardini, P Ulivi… - International Journal of …, 2020 - mdpi.com
epigenetic events involved in gastric cancer development. We conclude with a discussion of
new promising epigenetic … driver epigenetic mechanisms could be targeted as a therapeutic

Advances in epigenetics in systemic sclerosis: molecular mechanisms and therapeutic potential

PS Tsou, J Varga, S O'Reilly - Nature Reviews Rheumatology, 2021 - nature.com
… The three epigenetic mechanisms of DNA methylation, histone modifications and non-… )
pathogenesis, including fibroblasts. The main findings related to these epigenetic mechanisms in …

[HTML][HTML] Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential

KT Jurdziński, J Potempa, AM Grabiec - Clinical epigenetics, 2020 - Springer
… by epigenetic mechanisms and their clinical implications. … Although the key roles of histone
methylation, in particular … [41], the therapeutic potential of compounds that modulate this …

[HTML][HTML] Pathogenesis of ischemic stroke: role of epigenetic mechanisms

R Stanzione, M Cotugno, F Bianchi, S Marchitti, M Forte… - Genes, 2020 - mdpi.com
Epigenetic mechanisms can regulate different physiological processes that occur in a living
… types of epigenetic mechanisms and their involvement in the pathogenesis of IS (Figure 1). …

[HTML][HTML] Epigenetic susceptibility to severe respiratory viral infections and its therapeutic implications: a narrative review

E Crimi, G Benincasa, N Figueroa-Marrero… - British Journal of …, 2020 - Elsevier
… The interaction of viruses with host cells can cause perturbations of transcriptional
programmes involving such epigenetic mechanisms leading to viral shedding and inadequate …

[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
… by epigenetic mechanisms. Overall, this reciprocal interaction between the miRNAs and
the epigenetic … Comprehensive knowledge of the miRNA-epigenetic dynamics in cancer is …

[HTML][HTML] Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Epigenetics refers to all heritable changes in gene regulation without altering DNA sequencing.
The primary epigenetic mechanism … modulated through epigenetic mechanisms such as …

Epigenetics of colorectal cancer: biomarker and therapeutic potential

G Jung, E Hernández-Illán, L Moreira… - Nature reviews …, 2020 - nature.com
… , single-stranded RNA species that, given their emerging roles in CRC, are a major focus of
this Review 8 . They function as post-transcriptional repressors by binding to complementary …

[HTML][HTML] Epigenetic and breast cancer therapy: promising diagnostic and therapeutic applications

G Sher, NA Salman, AQ Khan, KS Prabhu… - Seminars in cancer …, 2022 - Elsevier
… Dysregulated methylation of DNA is an important reversible epigenetic mechanism associated
with BC pathogenesis via deregulated expression of genes. These genes are critical in …

[HTML][HTML] The epigenetic implication in coronavirus infection and therapy

S Atlante, A Mongelli, V Barbi, F Martelli, A Farsetti… - … epigenetics, 2020 - Springer
… Indeed, prolonged exposure to altered metabolic conditions may epigenetically affect
human cells [35]. Several epigenetic mechanisms work together to regulate gene expression …