… RA-FLSs was characterized by high expression levels of SUMO-1 and MMP-1, and low
expression levels of SENP1… the up-regulated SENP5 or SENP7, or down-regulated SENP1, they …

… are also considered epigenetic regulatory mechanisms. … of MMP-1 and SUMO-1 and also
low expression of SENP1 (… of SENP1 showed a decreased acetylation of H4 in the MMP-1 …

… SUMOylation is also implicated in the epigenetic regulation of osteogenesis. In human dental
… SENP1 attenuates rheumatoid arthritis by suppressing MMP1 expression. SUMOylation of …

… SUMOylation is also implicated in the epigenetic regulation of … Rheumatoid arthritis (RA) is
a chronic systemic, inflammatory … in RA comes from the finding that expression of the SENP1 …

… In line with these reports, the expression of the SENP1 desumoylase is decreased in RA …
Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression. …

… in rheumatoid arthritis (RA). Increased glycolysis in … deacetylase 4 on the MMP-1 promoter,
inhibiting MMP-1 levels (20). … expression of p-PKM2 in FLSs and ST from patients with RA. …

… Lamin B1 deficiency has been associated with epigenetic as … the ECM-degrading proteins,
MMP-1 and MMP-13, which led … that Piezo1 might control SENP1 expression, carry out the de-…

… to RA, as we previously reported on changes in expression … A final control was then added,
with 100% methylated control … We chose the qMSP technology for an epigenetic biomarker …

… diseases, such as lupus, rheumatoid arthritis, type 1 diabetes, … MMP-1 and Il6 genes, resulting
in accumulation of MMP-1 … IRAK1 and TRAF6 expression in PBMCs from RA patients and …

… We describe the role of the epigenetic regulation of Notch … , including MMP-1 and MMP-13,
causing RA joint inflammation and … Endothelial SENP1 deletion significantly abrogates retinal …