Amyloid-β: a potential link between epilepsy and cognitive decline

M Romoli, A Sen, L Parnetti, P Calabresi… - Nature Reviews …, 2021 - nature.com
… , with substantial uncertainties about whether epilepsy drives cognitive decline or vice versa,
… review evidence that amyloid-β (Aβ) forms part of a shared pathway between epilepsy and …

[PDF][PDF] Clarifying the role of D1 receptor signalling in Alzheimer's-related epilepsy commentary on Szabo et al.(2024)

M D'Amelio, C Costa - EJN. EUROPEAN JOURNAL OF …, 2024 - researchgate.net
D1 receptor protein expression. We discussed the observed increase of D1 receptor exposure
as a possibleAmyloid-β: A potential link between epilepsy and cognitive decline. Nature …

[HTML][HTML] Epilepsy in neurodegenerative diseases: related drugs and molecular pathways

A Cano, E Fonseca, M Ettcheto, E Sánchez-López… - Pharmaceuticals, 2021 - mdpi.com
… involved in AD pathogenesis have been described [19]. … Thus, the increase in amyloid-β
(Aβ) and tau peptide levels … development, whereas the D1 family appears to activate a …

Neurodegenerative pathways as targets for acquired epilepsy therapy development

PM Casillas‐Espinosa, I Ali, TJ O'Brien - Epilepsia Open, 2020 - Wiley Online Library
receptor activation has been linked epilepsy.119 In acquired … APP and amyloid-β production,
the prevention of amyloid-β … to prevent the development of epilepsy.224 The modulation of …

Sleep disorders and late-onset epilepsy of unknown origin: Understanding new trajectories to brain amyloidopathy

C Liguori, M Spanetta, M Romoli, F Placidi… - Mechanisms of ageing …, 2021 - Elsevier
… has been linked to epileptic seizures epileptic seizures, with beta … relationship between beta
amyloid and epilepsy: i) seizures … stage, ii) epileptic activity accelerates cognitive decline in …

[HTML][HTML] Mechanisms involved in epileptogenesis in Alzheimer's disease and their therapeutic implications

M Altuna, G Olmedo-Saura, M Carmona-Iragui… - International journal of …, 2022 - mdpi.com
… prevalent in epileptic patients than in elderly patients without epilepsy. Notwithstanding their
clinical significance, the diagnosis of clinical seizures in … These mechanisms are linked to …

Epilepsy in Neurodegenerative Diseases: Related Drugs and Molecular Pathways

A Cano Fernández, E Fonseca… - … , 2021, vol. 14, num …, 2021 - diposit.ub.edu
… involved in AD pathogenesis have been described [19]. … Thus, the increase in amyloid-β
(Aβ) and tau peptide levels … of D1 receptors in patients with refractory epilepsy promoted the …

[HTML][HTML] Epilepsy and Alzheimer's Disease: current concepts and treatment perspective on two closely related pathologies

A Leo, M Tallarico, M Sciaccaluga… - Current …, 2022 - ncbi.nlm.nih.gov
… , implicated also in AD pathogenesis, have been shown to … on the stimulation of D1 dopamine
receptor signaling, involving … seizures in AD patients is linked to the probability of seizure

The Homer1 family of proteins at the crossroad of dopamine-glutamate signaling: An emerging molecular “Lego” in the pathophysiology of psychiatric disorders. A …

A de Bartolomeis, A Barone, EF Buonaguro… - Neuroscience & …, 2022 - Elsevier
… , organization of dendritic spines’ growth, as well as meta- and homeostatic plasticity control
are only a few of the multiple endocellular and synaptic functions that have been linked to …

[HTML][HTML] On the relationships between epilepsy, sleep, and Alzheimer's disease: A narrative review

JM Hanke, KA Schindler, A Seiler - Epilepsy & Behavior, 2022 - Elsevier
… the glymphatic system in the pathogenesis of epilepsy although it has yet not been clearly
linked. … Sleep, AD, and epilepsy were linked in different ways throughout the articles we have …