… brain activity after injury to further understand caffeine neuroprotection. Rat dams received
caffeine … This method was used for all groups regardless of caffeine treatment, and hypoxia …

… Caffeine had a proconvulsant effect and resulted in less oxygen fluctuations in the hippocampus…
Regarding possible postictal hypoxia or hyperoxia in neonatal rats with febrile seizures, …

… In addition, epileptogenic alterations during the … - hypoxia and consequently death, since
responses at brain level depend intrinsically on the supply of oxygen by the blood, but during …

… followed by a brief period of hypoxia in neonatal rats (P7). This … neurogenesis in neonatal
rats [287], possibly due to caffeine’… role in epileptogenesis following an insult to the infant brain. …

… be affected by caffeine in rats, with increased synaptic activity in vitro and … rat model of global
hypoxia, flupirtine was shown to dose-dependently stop behavioral seizures during hypoxia …

… Cerebral hypoxia likely contributes to the pathophysiology of … caffeine was administered after
the onset of seizure activity in … only transiently in a pre-epileptic brain are not expected to be …

… : Postictal hypoxia follows seizure termination in the hippocampus … Another way of describing
an epileptic brain is one in which the … We have also determined that the drug caffeine, an …

… drug for other anti-epileptic medications, it has shown … of HIE, caffeine helps reduce white
matter brain injury [124]. … after cerebral hypoxia-ischemia in neonatal rats reduces brain edema …

… It not only controls seizures (ictogenesis), but also plays a major role in processes that
turn a normal brain into an epileptic brain (epileptogenesis). It is involved in the control of …

… In conclusion, there is a distinct lack of high-quality evidence for whether and to what
extent neonatal seizures exacerbate brain damage after hypoxia-ischemia and how best to …