[HTML][HTML] Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment
E Schoutrop, L Moyano-Galceran, S Lheureux… - Seminars in cancer …, 2022 - Elsevier
… the field of cancer, the majority of patients with ovarian cancer are still … knowledge in epithelial
ovarian cancer development and … experimental models used to develop novel therapies. …
ovarian cancer development and … experimental models used to develop novel therapies. …
Current insights into the metastasis of epithelial ovarian cancer-hopes and hurdles
… cells to the omentum and metastatic colonization to peritoneal adipose in experimental
models [140]. Milky spots are composed of cellular aggregations of mesenchymal cells, including …
models [140]. Milky spots are composed of cellular aggregations of mesenchymal cells, including …
Treatment of epithelial ovarian cancer
L Kuroki, SR Guntupalli - Bmj, 2020 - bmj.com
… A preliminary paper in Nature BME reported efficacy in tumor reduction in mouse models of
ovarian cancer.Although these data are promising, CAR-T remains in its infancy for treatment …
ovarian cancer.Although these data are promising, CAR-T remains in its infancy for treatment …
[PDF][PDF] Developing organoids from ovarian cancer as experimental and preclinical models
N Maenhoudt, C Defraye, M Boretto, Z Jan… - Stem Cell Reports, 2020 - cell.com
… Etiology and site of origin of EOC, whether it is ovarian surface epithelium (OSE) or fallopian
… experimental and preclinical EOC models are needed. A powerful research tool to model …
… experimental and preclinical EOC models are needed. A powerful research tool to model …
Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axis
S Bu, Q Wang, J Sun, X Li, T Gu, D Lai - Cell death & disease, 2020 - nature.com
… a The schematic graph of establishing chronic restraint stress (CRS) animal models in
this study. b ELISA was used to evaluate the effects of CRS on nude mice by examining the …
this study. b ELISA was used to evaluate the effects of CRS on nude mice by examining the …
Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy
… We engineered a panel of murine fallopian tube epithelial cells bearing mutations typical …
ovarian cancer using immunocompetent animal models. Unfortunately, the preclinical models …
ovarian cancer using immunocompetent animal models. Unfortunately, the preclinical models …
Epithelial ovarian cancer and the immune system: biology, interactions, challenges and potential advances for immunotherapy
… Vasculogenic mimicry has been shown to increase in a preclinical model of ovarian cancer
in response to treatment with bevacizumab [131], although the chosen cell line (SKOV3) is …
in response to treatment with bevacizumab [131], although the chosen cell line (SKOV3) is …
[PDF][PDF] Mouse ovarian cancer models recapitulate the human tumor microenvironment and patient response to treatment
E Maniati, C Berlato, G Gopinathan, O Heath… - Cell reports, 2020 - cell.com
… These models are syngeneic in FVB mice and originate from the ovarian surface epithelium.
Following intraperitoneal (ip) injection, they produced extensive omental and peritoneal …
Following intraperitoneal (ip) injection, they produced extensive omental and peritoneal …
The role of myeloid-derived suppressor cells in increasing cancer stem-like cells and promoting PD-L1 expression in epithelial ovarian cancer
N Komura, S Mabuchi, K Shimura, E Yokoi… - Cancer Immunology …, 2020 - Springer
… study, using clinical samples, ovarian cancer cell lines and a mouse model of ovarian …
epithelial ovarian cancer A total of 340 patients with surgically staged epithelial ovarian cancer …
epithelial ovarian cancer A total of 340 patients with surgically staged epithelial ovarian cancer …
Immunotherapy advances for epithelial ovarian cancer
EG Hartnett, J Knight, M Radolec, RJ Buckanovich… - Cancers, 2020 - mdpi.com
… /− immunocompetent murine model of high-grade serous ovarian cancer. Evidence from this
… Clinical translation of results obtained from animal models has been met with mixed success…
… Clinical translation of results obtained from animal models has been met with mixed success…
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