[HTML][HTML] The role of PI3K/AKT and MAPK signaling pathways in erythropoietin signalization
Z Tóthová, M Šemeláková, Z Solárová, J Tomc… - International Journal of …, 2021 - mdpi.com
… erythropoiesis is also regulated by synergic activation of EPOR and transferrin receptors 2
(TFR2), mediating signal … ectopic bone formation [90]. The proliferation and migration ability of …
(TFR2), mediating signal … ectopic bone formation [90]. The proliferation and migration ability of …
[HTML][HTML] Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss
M Rauner, M Murray, S Thiele, D Watts, D Neumann… - Bone Research, 2021 - nature.com
… of Epo lose bone mass due to suppressed bone formation … in regulating osteoblast function
and osteoblast-mediated … osteoblastogenesis via mTOR and Ephrin B2/EphB4 signaling. In …
and osteoblast-mediated … osteoblastogenesis via mTOR and Ephrin B2/EphB4 signaling. In …
The opposing roles of the mTOR signaling pathway in different phases of human umbilical cord blood-derived CD34+ cell erythropoiesis
Q Liu, L Luo, C Ren, M Zou, S Yang, B Cai, L Wu… - Stem Cells, 2020 - academic.oup.com
… the maturation phase of erythropoiesis, mTOR inhibition … mTOR in regulating different
phases of human erythropoiesis… Our findings of divergent inputs from mTOR signaling during …
phases of human erythropoiesis… Our findings of divergent inputs from mTOR signaling during …
Erythropoietin regulates signaling pathways associated with neuroprotective events
CM Sergio, CA Rolando - Experimental brain research, 2022 - Springer
… effects, and its mechanisms of signal transduction pathways are defined, and there is a … of
Erythropoietin and its relationship with HIF1, PI3/Akt, GSK3B, JAK/STAT, and MAPKs signaling …
Erythropoietin and its relationship with HIF1, PI3/Akt, GSK3B, JAK/STAT, and MAPKs signaling …
[HTML][HTML] mTOR inhibitors induce erythropoietin resistance in renal transplant recipients
R Jefferies, H Puttagunta, A Krishnan, A Irish… - Frontiers in …, 2022 - frontiersin.org
… (EPO) resistance induced by mTOR inhibitors as a potential cause of SIA (14–16). … the role
of mTOR inhibitors on iron, hepcidin and erythropoietin-mediated regulation of hemopoiesis …
of mTOR inhibitors on iron, hepcidin and erythropoietin-mediated regulation of hemopoiesis …
[HTML][HTML] Effects of erythropoietin in white adipose tissue and bone microenvironment
S Suresh, J Lee, CT Noguchi - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
… erythropoiesis and showed that cerebral EPO regulation of … and decreased bone formation
or bone loss. However, while … and RAW264.7 cells was mTOR signaling dependent, but the …
or bone loss. However, while … and RAW264.7 cells was mTOR signaling dependent, but the …
Erythropoietin-induced autophagy protects against spinal cord injury and improves neurological function via the extracellular-regulated protein kinase signaling …
L Zhong, H Zhang, ZF Ding, J Li, JW Lv, ZJ Pan… - Molecular …, 2020 - Springer
… The cavity ratio, number of motor neurons, and TUNEL+ cells in the EPO group were mimicked
by EGF, and the effect of EPO on the cavity ratio, number of motor neurons, and number …
by EGF, and the effect of EPO on the cavity ratio, number of motor neurons, and number …
[HTML][HTML] The many facets of erythropoietin physiologic and metabolic response
S Suresh, PK Rajvanshi, CT Noguchi - Frontiers in physiology, 2020 - frontiersin.org
… the protective effects of EPO in ischemic injury and wound healing, regulation of metabolic
… that reduction in bone formation in these mice is related to loss of EPO response in …
… that reduction in bone formation in these mice is related to loss of EPO response in …
[HTML][HTML] HIF-1α regulates glucocorticoid-induced osteoporosis through PDK1/AKT/mTOR signaling pathway
WN Xu, HL Zheng, RZ Yang, LS Jiang… - Frontiers in …, 2020 - frontiersin.org
… regulated the negative effects of glucocorticoid on osteogenic function via the PDK1/AKT/mTOR
signaling pathway… has a deleterious effect on bone formation. Increased concentration of …
signaling pathway… has a deleterious effect on bone formation. Increased concentration of …
Effect of erythropoietin on calcification of vascular smooth muscle cells and its molecular regulatory mechanism
X Li, X Jiang, F He, Y Xia, X Chen, X Du… - Journal of Cardiovascular …, 2021 - Springer
… In this study, we noticed that EPO promoted the expression of bone formation–related genes
(BMP2, RUNX2, OPN, and OCN), and the expression of the transcription factor GATA6 was …
(BMP2, RUNX2, OPN, and OCN), and the expression of the transcription factor GATA6 was …