[HTML][HTML] 17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin
AL Frump, M Albrecht, B Yakubov… - The Journal of …, 2021 - Am Soc Clin Investig
… We previously showed that E2 and ER-α agonist treatment are RV protective in rat models
of pulmonary hypertension–induced RVF and that ER-α abundance correlates with improved …
of pulmonary hypertension–induced RVF and that ER-α abundance correlates with improved …
Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats
TC Cheng, JL Philip, DM Tabima… - … Physiology-Heart …, 2020 - journals.physiology.org
… Estradiol improves right ventricular function in rats with severe angioproliferative
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
Estrogen Receptor-α Exerts Endothelium-Protective Effects and Attenuates Pulmonary Hypertension
AL Frump, B Yakubov, A Walts, A Fisher… - … Journal of Respiratory …, 2023 - atsjournals.org
… Estradiol improves right ventricular function in rats with severe angioproliferative
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
[HTML][HTML] Exogenous estrogen preserves distal pulmonary arterial mechanics and prevents pulmonary hypertension in rats
JL Philip, DM Tabima, GD Wolf, AL Frump… - … Journal of Respiratory …, 2020 - atsjournals.org
… Estradiol improves right ventricular function in rats with severe angioproliferative
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
[HTML][HTML] Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid …
… Estradiol improves right ventricular function in rats with severe angioproliferative
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol …
… of severe pulmonary arterial hypertension in response to vascular endothelial growth factor receptor 2 blockade in a genetically prone rat model is reduced by female …
KR Chaudhary, Y Deng, A Yang… - … of the American Heart …, 2021 - Am Heart Assoc
… lung endothelial cell apoptosis or improve PAH phenotype. … , right ventricular (RV) pressure
overload leads to right‐sided … with estradiol or progesterone in female rats abolished the lung …
overload leads to right‐sided … with estradiol or progesterone in female rats abolished the lung …
[HTML][HTML] Emerging therapies for right ventricular dysfunction and failure
A Klinke, T Schubert, M Müller… - Cardiovascular …, 2020 - ncbi.nlm.nih.gov
… in the context of pulmonary arterial hypertension (PAH), … rat model attenuated PA
remodeling was linked to an inhibition of aromatase transcription, resulting in decreased estrogen …
remodeling was linked to an inhibition of aromatase transcription, resulting in decreased estrogen …
MECHANISMS OF SEX DIFFERENCES IN RIGHT (-SIDED) HEART FAILURE: ROLE OF ANGIOGENESIS
E Seelemann - 2022 - dalspace.library.dal.ca
… CDF rats and the pulmonary artery banding (PAB) model. … right ventricle (RV), the chamber
that forms the bottom right … the role of estradiol in the adaptations observed in female rats…
that forms the bottom right … the role of estradiol in the adaptations observed in female rats…
Ormeloxifene, a selective estrogen receptor modulator, protects against pulmonary hypertension
AO Abdulkareem, P Tiwari, ZR Lone, H Iqbal… - European Journal of …, 2023 - Elsevier
… 17β-estradiol and uterine weight in ovary-intact rats. Further, … estrogen receptors α and
β, increasing right ventricular … Right ventricular dysfunction is a key determinant of disease …
β, increasing right ventricular … Right ventricular dysfunction is a key determinant of disease …
Effect of estrogen receptor α on cardiopulmonary adaptation to chronic developmental hypoxia in a rat model
NT Severyn, P Esparza, H Gao… - … of Physiology-Lung …, 2024 - journals.physiology.org
… Right ventricle adaptation was maintained in the setting of hypoxia. While no major … that
the increase in lung volume induced by 133 high-altitude exposure is due to an increase in the …
the increase in lung volume induced by 133 high-altitude exposure is due to an increase in the …