Protective effect of liquiritin on coronary heart disease through regulating the proliferation of human vascular smooth muscle cells via upregulation of sirtuin1

L Yuan, D Wang, C Wu - Bioengineered, 2022 - Taylor & Francis
cell proliferation, migration, and apoptosis in ox-LDL-induced hVSMCs In conclusion, liquiritin
plays a protective role in coronary heart disease … can alleviate endothelial cell dysfunction …

[HTML][HTML] ET-1 regulates the human umbilical vein endothelial cell cycle by adjusting the ERβ/FOXN1 signaling pathway

Y Wang, Y Ruan, S Wu - Annals of Translational Medicine, 2020 - ncbi.nlm.nih.gov
… of estrogen are primarily mediated by intracellular estrogen … for vascular endothelial
cell oxidative stress (28) and apoptosis (… reduce vascular remodeling and ischemia by up-regulating

Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature

SA Sabe, J Feng, FW Sellke… - … of Physiology-Heart and …, 2022 - journals.physiology.org
… In an in vitro setting of cultured human coronary artery endothelial cells, estrogen
exposure results in increased eNOS and NO release from endothelial cells (210). Estrogen

Echinacoside‑induced nitric oxide production in endothelial cells: Roles of androgen receptor and the PI3K‑Akt pathway

L Gu, D Lian, Y Zheng, W Zhou… - … Journal of Molecular …, 2020 - spandidos-publications.com
… The long double-stranded RNAs were synthesized by the target mRNA of the AR and estrogen
… through which ECH exerts its pharmacological effects to prevent cardiovascular disease. …

[PDF][PDF] Estradiol Inhibits Human Brain Vascular Pericyte Migration Activity: A Functional and Transcriptomic Analysis. Cells 2021, 10, 2314

L Kurmann, M Okoniewski, RK Dubey - 2021 - scholar.archive.org
… with endothelial cells, we assessed whether estradiol improvesestrogen and estrogen
receptors in cardiovascular disease … microvascular pericytes by up-regulating the expression of …

Qixian granule inhibits ferroptosis in vascular endothelial cells by modulating TRPML1 in the lysosome to prevent postmenopausal atherosclerosis

M Zhang, C Mao, Y Dai, X Xu, X Wang - Journal of Ethnopharmacology, 2024 - Elsevier
… ferroptosis in vascular endothelial cells through up-regulating GPER/… attributed to the
cardiovascular protective effect of estrogen, although its … Coronary heart disease in women …

LncRNA-mediated Modulation of Endothelial Cells: Novel Progress in the Pathogenesis of Coronary Atherosclerotic Disease

S Ouyang, ZX Zhou, HT Liu, Z Ren… - Current Medicinal …, 2024 - ingentaconnect.com
… (CAD) is a common cardiovascular disease and an important … EZR-AS1 overexpression
increased apoptosis, proliferation, and … tion of expression and function of the estrogen receptor. …

[HTML][HTML] Sex differences, estrogen metabolism and signaling in the development of pulmonary arterial hypertension

Y Sun, S Sangam, Q Guo, J Wang, H Tang… - … in Cardiovascular …, 2021 - frontiersin.org
… Reversing fibrosis and up-regulating the expression of new … of apoptosis, thereby slowing
the progression of heart failure, … aortic SMCs (152) and rat liver epithelial cell lines (153), the …

Association of endometriosis with cardiovascular disease: Genetic aspects

L Papageorgiou, D Chaniotis… - International …, 2023 - search.proquest.com
… , with endothelial cells (ECs), smooth muscle cells (SMCs) … and rs13394619 in growth
regulating estrogen receptor binding 1 … in programmed cell death (apoptosis), cell cycle regulation, …

Menopause-Related Estrogen Decrease and the Pathogenesis of HFpEF: JACC Review Topic of the Week

AR Sabbatini, G Kararigas - Journal of the American College of Cardiology, 2020 - jacc.org
endothelial cells, thereby promoting vasodilation at supraphysiological concentrations in
human coronary arteries (… oxidative stress-induced endothelial cell apoptosis (66). In addition, …