17β-estradiol in colorectal cancer: friend or foe?
Z Wu, C Xiao, J Wang, M Zhou, F You, X Li - Cell Communication and …, 2024 - Springer
… breast cancer cells, ERβ suppresses around … levels in CRC compared to normal tissues
[16, 26]. Conversely, ERα is expressed at much lower levels than ERβ in normal colonic mucosal …
[16, 26]. Conversely, ERα is expressed at much lower levels than ERβ in normal colonic mucosal …
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular …
G Chen, H Zeng, X Li, J Liu, Z Li, R Xu, Y Ma… - Cell death & …, 2021 - nature.com
… reduced the intestinal histological damage, weight loss, and mucosal barrier dysfunction, …
Tight junction proteins connecting adjacent IECs and mucosal components secreted by …
Tight junction proteins connecting adjacent IECs and mucosal components secreted by …
Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment
L Wenxuan, L Liu, L Zhang, Z Qiu, Z Wu… - Frontiers in …, 2023 - frontiersin.org
… to the lives and health of people around the world, and is a … protein levels on both healthy
and cancerous colon mucosa (… and progesterone receptor antagonists inhibit colorectal cancer …
and cancerous colon mucosa (… and progesterone receptor antagonists inhibit colorectal cancer …
Therapeutic strategies and potential actions of female sex steroid hormones and their receptors in Colon cancer based on preclinical studies
AA Mahbub - Life, 2022 - mdpi.com
… , progesterone receptor, endogenous expression of estrogen receptor, endogenous expression
of progesterone receptor, … with their corresponding adjacent normal colon tissues. Others …
of progesterone receptor, … with their corresponding adjacent normal colon tissues. Others …
[PDF][PDF] Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities.
G Topi - 2020 - portal.research.lu.se
… Around eight hundred thousand people are diagnosed with CRC each year. Regarding the
… of this enzyme are expressed to high extend in the normal colon mucosa, but its expression …
… of this enzyme are expressed to high extend in the normal colon mucosa, but its expression …
Somatostatin and its receptor system in colorectal cancer
A Kasprzak - Biomedicines, 2021 - mdpi.com
… status of estrogen and progesterone receptors was observed [… SST5 in normal colon and
colorectal cancer tissue samples … with adjacent normal mucosa (unpublished data) (Figure 2). …
colorectal cancer tissue samples … with adjacent normal mucosa (unpublished data) (Figure 2). …
Delineating the role of nuclear receptors in colorectal cancer, a focused review
… Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
Estrogen receptor function: impact on the human endometrium
K Yu, ZY Huang, XL Xu, J Li, XW Fu… - Frontiers in …, 2022 - frontiersin.org
… estrogen receptors (ERs) to induce mucosal proliferation during the proliferative phase and
progesterone receptor … subpopulation of ERs located in or adjacent to the plasma membrane; …
progesterone receptor … subpopulation of ERs located in or adjacent to the plasma membrane; …
Protumor role of estrogen receptor expression in oral squamous cell carcinoma cells
R Akyu, K Tomihara, M Yamazaki… - Oral Surgery, Oral …, 2021 - Elsevier
… gingiva, floor of mouth, and buccal mucosa revealed that ERβ was detected in the cytoplasm
… In some normal epithelia adjacent to the carcinoma, positive staining for ERβ was localized …
… In some normal epithelia adjacent to the carcinoma, positive staining for ERβ was localized …
Investigating the protective role of the novel oestrogen receptor GPER in colorectal cancer
M Abancéns - 2022 - repository.rcsi.com
… Progesterone has also been considered as a potential contributor to CRC protection. In
general, normal serum progesterone levels … of oestrogen receptors in the intestinal mucosa of …
general, normal serum progesterone levels … of oestrogen receptors in the intestinal mucosa of …