Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α

M Böckers, NW Paul, T Efferth - Toxicology and Applied Pharmacology, 2020 - Elsevier
… about the molecular effects of BPA and its analogues in the cell… than 200 genes unrelated to
ESR1, we only show those with … evaluated the effect of the four bisphenolic compounds BPA, …

Evaluation of the cytotoxic effect of bisphenol A and its analogs in MCF-7 and HSeC cell lines in vitro

S İpek, İ İyigündoğdu, A Üstündağ… - Fabad Journal of …, 2022 - dergipark.org.tr
… The cells within DMSO were used as a solvent control group. … disrupting effects of bisphenol
analogues by employing MCF7 … , teratogenic, and estrogenic effects of bisphenol A and its …

[HTML][HTML] Transcriptome analysis of human mammary epithelial cells treated with bisphenol A and bisphenol a analogue mixtures reveals major alterations in multiple …

R Mesnage, H Omriouate… - Public Health …, 2022 - publichealthtoxicology.com
… In this study, the action of BPA and a mixture of BPA-analogues … lines, estrogen receptor
positive MCF-7 and MCF-12A, and … assays show limited effects from bisphenols on MCF-7, MCF-…

Effect of bisphenols on telomerase expression and activity in breast cancer cell lines

Z Awada, R Nasr, R Akika, A Ghantous, L Hou… - Molecular Biology …, 2020 - Springer
… The estrogenic activity of BPF is comparable to that of BPA, … -wide effects of BPA and its
analogues in MCF-7 and MDA-MB… by our group and other researchers in MCF-7 cells treated by …

An in vitro investigation of endocrine disrupting potentials of ten bisphenol analogues

J Lin, L Deng, M Sun, Y Wang, S Lee, K Choi, X Liu - Steroids, 2021 - Elsevier
… cancer cells MCF-7 with the estrogen-receptor alpha (ERα) controlled luciferase reporter
gene. … BPB, BPM and BPAP did not show proliferation effects within the concentration range. …

[HTML][HTML] The mixture effects of bisphenol derivatives on estrogen receptor and androgen receptor

C Park, H Song, J Choi, S Sim, H Kojima, J Park… - Environmental …, 2020 - Elsevier
… , AR and AhR activities of mixtures of bisphenol analogues. … The human breast
adenocarcinoma MCF-7 cells cultured in … We compared each group using one-way analysis of …

[HTML][HTML] Bisphenol-A analogue (bisphenol-S) exposure alters female reproductive tract and apoptosis/oxidative gene expression in blastocyst-derived cells

A Nourian, A Soleimanzadeh, AS Jalali… - Iranian Journal of Basic …, 2020 - ncbi.nlm.nih.gov
BPA mimics an estrogenic effect by binding competitively to … The details of gene specific
sequence primers are shown in … observed by ER α in normal MCF-7 breast cancer cell lines (90, …

A gene expression biomarker identifies chemical modulators of estrogen receptor α in an MCF-7 microarray compendium

J Rooney, N Ryan, J Liu, R Houtman… - Chemical research in …, 2021 - ACS Publications
… the nucleoside analogue and transcriptional inhibitor … collection in MCF-7 cells identified
chemicals not previously recognized as ERα modulators. Of the 1153 chemicals in the collection

Hormone effects of eighteen bisphenol analogues and their effects on cellular homeostasis and the typical signal pathways

M Ma, D Guo, R Wang, P Wang, X Su - Environmental Pollution, 2023 - Elsevier
… to show certain toxicological effects, especially, estrogen and … hormone effect of the eighteen
typical bisphenol analogues … the estrogen-like effect of BPs when exposure to MCF-7 cells …

[HTML][HTML] Mixture Effects of Bisphenol A and Its Structural Analogs on Estrogen Receptor Transcriptional Activation

H Lee, J Park, K Park - Toxics, 2023 - mdpi.com
… , several BPA analogs exhibited estrogenic activity in the human breast cancer cell line MCF-7
[… are the structural analogs of BPS, did not show agonistic activity but showed antagonistic …