Potential of Piper spp. as a source of new compounds for the leishmaniases treatment

JF Peixoto, YJ Ramos, D de Lima Moreira… - Parasitology …, 2021 - Springer
… Among neolignans evaluated, eupomatenoid-5 (9) showed … (L.) amazonensis
promastigotes, with IC 50 ranging from 2.5 … (5), isolated from the ethanolic extract of leaves of P. …

[HTML][HTML] Natural compounds based chemotherapeutic against Chagas disease and leishmaniasis: Mitochondrion as a strategic target

D Lazarin-Bidóia, FP Garcia… - Memórias do Instituto …, 2022 - SciELO Brasil
Eupomatenoid-5 isolated from leaves of Piper regnellii induces apoptosis in Leishmania
amazonensis. Evid Based Complement … Eupomatenoid-5 isolated from leaves of Piper regnellii

[PDF][PDF] Mini-Review on Phytochemistry and Pharmacological Studies of Piper regnellii (Miq.) C. DC.

WMNHW Salleh, A Tawang, MH Jauri - 2021 - biointerfaceresearch.com
induces apoptosis in Leishmania amazonensis. Evid. Based Complement. … Evaluation of
antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii

Antileishmanial Activity of the Genus Piper: A Systematic Review

EO Silva, KCF Castro… - European Journal of …, 2021 - research.manuscritpub.com
… (L.) amazonensis, two chalcones demonstrated strong … of the genus Piper have potential
activity against leishmaniasis. We … eupomatenoid-5, a compound isolated from leaves of Piper

Emerging Phytochemicals to Treat Leishmaniasis: A Review of Experimental Studies from 2011 to 2021

M Namdeo, J Veronica, K Kumar… - Current Bioactive …, 2024 - ingentaconnect.com
… metabolism of the parasite and causes apoptotic-like cell death [31, … Eupomatenoid-5, a
neolignan extracted from leaves of Piperamazonensis by inducing incidental death markers and …

Versatile Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antileishmanial Drugs

PO Sakyi, RK Amewu, RNOA Devine… - … : Opportunities and …, 2023 - Springer
… It has also been reported to induce apoptosis with changes … Ancistrogriffine A, 73 isolated
from the leaves and twigs of … of eupomatenoid-5, 88 from leaves of Piper regnellii displayed a …

[HTML][HTML] Piper aduncum essential oil: a promising insecticide, acaricide and antiparasitic. A review

A Durofil, M Radice, J Blanco-Salas, T Ruiz-Téllez - Parasite, 2021 - ncbi.nlm.nih.gov
… crassinervium with trypanocidal activity [56]; and eupomatenoid-5 isolated from leaves of
P. regnellii which induces apoptosis in Leishmania amazonensis [36]. …

The potential of traditional knowledge to develop effective medicines for the treatment of leishmaniasis

LFD Passero, ES Brunelli, T Sauini… - Frontiers in …, 2021 - frontiersin.org
… extracts produced with the leaves, roots and aerial parts of Piper sanguineispicum Trel., …
isolated compound dehydrozaluzanin C showed in vitro activity against L. (L.) amazonensis

Activity of Piperaceae extracts and fractions in the control of Phytomonas serpens

NS Cancini, J Beraldo-Borrazzo, JL Menezes… - Ciência Rural, 2020 - SciELO Brasil
Eupomatenoid-5 Isolated from Leaves of Piper regnellii Induces Apoptosis in Leishmania
amazonensis. Evidence-Based Complementary and Alternative Medicine, 2013. Available from…

Promising antimicrobial agents from some Latin American medicinal plants against disease-causing pathogens in humans and animals

A Muñoz-Acevedo, MC González, OJ Castillo… - … from Natural Products, 2022 - Springer
regnellii leaves presented a significant activity against the … isolated neolignans,
eupomatenoid-3 (1) and eupomatenoid-… antileishmanial activity against Leishmania amazonensis, …