… servers to the same workflow on their own servers in the highly admixed South African
population, … To estimate the accuracy of imputation in terms of comparing imputed with sequenced …

… software currently has a significant impact on accuracy [34]. … In this study, we evaluate the
latest versions of the most … a reference panel containing admixed populations, increasing chip …

… Evaluating the accuracy of imputation methods in a five-way admixed population. … However,
these statistics do not provide an assessment of the accuracy of the imputed genotypes, and …

… human genetics in recent decades by providing a systematic … 28] to assess the concordance
rate between the imputed genotypes and … Ethnic specificity is critical in genetic research [34]. …

… Therefore, both imputation reliability and error rate were used to evaluate the … The use
of multiple populations to form a mixed reference population can effectively reduce genetic …

… (29, 31–34), such that admixed samples form a cline … for best practices for imputation in
admixed populations to be … assessing genetic effect sizes while controlling for the environment. …

… The few studies that have examined HLA imputation accuracy in African populations have
… This study aimed to evaluate HLA allele imputation accuracy in a West African population, …

… Comparison of the true and imputed genotypes revealed lower imputation accuracy for …
to evaluate the potential loss of statistical validity and power incurred by the use of imputed …

… imputation accuracy (23). Many studies have validated the accuracy and reliability of
imputation of rare variants (24,25), but the focus of most of these studies has been on populations …

… -frequency and rare variants, its accuracy is usually low [33,34,35] and mainly depends on …
(iv) two critical reviews on the quality assessment of imputation methods [17,24]. Seven out of …