Evaluation of the effect of a new oral contraceptive containing estetrol and drospirenone on hemostasis parameters
J Douxfils, C Klipping, I Duijkers, V Kinet, M Mawet… - Contraception, 2020 - Elsevier
Objective To assess the effect on hemostasis parameters of a new combined oral
contraceptive (COC). Study design In this randomized, single centre, open-label, exploratory
study, healthy women received either 15 mg estetrol/3 mg drospirenone (E4/DRSP)(n= 39),
30 mcg ethinylestradiol/150 mcg levonorgestrel (EE/LNG)(n= 30), or 20 mcg
ethinylestradiol/3 mg drospirenone (EE/DRSP)(n= 32) for six 28-day cycles. Blood was
collected at baseline, cycle 3, and cycle 6. Median change from baseline was evaluated for …
contraceptive (COC). Study design In this randomized, single centre, open-label, exploratory
study, healthy women received either 15 mg estetrol/3 mg drospirenone (E4/DRSP)(n= 39),
30 mcg ethinylestradiol/150 mcg levonorgestrel (EE/LNG)(n= 30), or 20 mcg
ethinylestradiol/3 mg drospirenone (EE/DRSP)(n= 32) for six 28-day cycles. Blood was
collected at baseline, cycle 3, and cycle 6. Median change from baseline was evaluated for …
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