… There is robust evidence that A 2A R antagonism attenuates … ) set at 250/ − 175 mV for a
sensitivity at 0.5 nA/V and the peak … Since PPADS has a low efficiency to antagonize P2X4R and …

… selectively in dentate granule cells reduced MF sprouting, most likely … evidence that A 2A
Rs, in particular those located in dentate granule cells are activated by ATP-derived adenosine …

… Indeed, the ATN system may have a high sensitivity but a low … review, amyloid-PET has a
sensitivity of 95% and a specificity … Indeed, all evidence remarqued in this review underline the …

… proof-of-concept studies that support A 2A R as credible targets and the clinical interest to
repurpose adenosine … subtypes, the A 2B R have lower affinity for adenosine. Finally, the A 3 R …

… , and recent clinical evidence suggests that this approach is … The increased sensitivity of
CD8+ T cells to adenosine was … In conclusion, the adenosine-A2AR signaling leads to the low …

… concentrations of adenosine are maintained at a low level as … Other evidence, supporting
the proinflammatory role of this … found to be significantly more susceptible to collagen-induced …

… a biomarker reflective of susceptibility and progression of … of A 2A receptors in KO (knockout)
mice, reduced hippocampal … an important proof-of-concept that A 2A receptor blockade …

… , with a very particular role of adenosine A 2A receptors (A 2A R… In contrast, the
evidence gathered by Rod Cunha at Alex … more alcohol and exhibit reduced sensitivity (ataxia/hypnosis) …

… The first proof of AR participation in bipolar disorders is … habits, the subject’s susceptibility
to anxiety, and the presence … of the low expression of these receptors in the areas of the brain …

… in dopaminergic receptors and/or dopaminergic sensitivity.341… of evidence suggests that
Ar and A2A-adenosine receptors … and is associated with reduced expression of messenger …