Frontiers | Staphylococcus aureus adaptive evolution: Recent insights on how immune
evasion, immunometabolic subversion and host genetics impact vaccine development Skip to …

… Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. … SAgs have evolved in parallel not only in different bacteria but also in viruses; the most …

… The purpose of this short review is to present the main studies of evolution of the S. aureus
… were also devoid of superantigens (enterotoxin and tst genes). Of note, the prevalence of …

… Staphylococcus aureus, causing multiple affections. This review summarizes the current
knowledge on every superantigen … Microorganisms evolve to evade the host immune system. All …

… that the superantigens (SAgs) are important virulence factors produced during severe
Staphylococcus aureus–… aureus has evolved to take advantage of a human immune system …

… aureus are specifically adapted to a narrow host range on a short evolutionary time scale. …
toxins, superantigens, host immune evasions elements, and adhesins than other non-…

… Staphylococcus aureus infection is a major public health threat in part due to the spread
of antibiotic resistance and repeated failures to develop a protective vaccine. Infection is …

… Genomic and epidemiological studies show that S. aureus has jumped between host species
many times over its evolutionary history. These jumps have involved the dynamic gain and …

… aureus adaptation to the CF airway over time, how strains evolve in response to antimicrobial
therapy, and whether S. aureus strains are shared between patients with CF remains …

… A phylogenetic tree based on the selw sequences indicates that selw evolution has
progressed largely in a lineage-specific manner (Fig. 1B). Of the isolates containing selw, 62.5%, …