[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage

Y Wan, KG Holste, Y Hua, RF Keep, G Xi - Neurobiology of disease, 2023 - Elsevier
Hematoma mass and clot retraction The intracerebral hematoma mass will cause brain swelling
… Increased ICP may impact cerebral blood flow (CBF) but the hematoma mass may also …

Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage

Z Li, M Li, SX Shi, N Yao, X Cheng, A Guo… - Journal of Experimental …, 2020 - rupress.org
… features in the brain after ICH, … and brain edema after ICH via cytotoxicity toward cerebral
endothelial cells and recruitment of neutrophils that augment focal inflammation. Thus, brain-…

Glymphatic Drainage Blocking Aggravates Brain Edema, Neuroinflammation via Modulating TNF-α, IL-10, and AQP4 After Intracerebral Hemorrhage in Rats

X Liu, G Wu, N Tang, L Li, C Liu, F Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
… system in intracerebral hemorrhage (ICH) and its protective mechanism. Method: Experimental
ICH … However, in this experiment, it was observed that cerebral glymphatic blocking only …

miR-7-5p affects brain edema after intracerebral hemorrhage and its possible mechanism

X Chen, S Deng, Q Lei, Q He, Y Ren… - Frontiers in Cell and …, 2020 - frontiersin.org
… In view of the close relationship between AQP4 and brain edema found in previous
experiments, we focused our research on whether the mechanism of NBP in reducing brain edema

[HTML][HTML] L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model

Z Zeng, X Gong, Z Hu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… In the follow-up experiment, we will use multiple doses to see whether NBP is dose-dependent
on the treatment of ICH. Third, female animals shall be utilized in future studies to …

Molecular, pathological, clinical, and therapeutic aspects of perihematomal edema in different stages of intracerebral hemorrhage

C Jiang, H Guo, Z Zhang, Y Wang, S Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
brain edema in 24 hours, but an increase in brain edemaBrain tissue with cerebral blood
flow below 10 mL/100 g × … and persisted for up to 7 days in experimental ICH models [14, 53]. …

Functional investigation of meningeal lymphatic system in experimental intracerebral hemorrhage

HH Tsai, YC Hsieh, JS Lin, ZT Kuo, CY Ho, CH Chen… - Stroke, 2022 - Am Heart Assoc
… Promotion of hematoma resolution in a timely manner reduces intracerebral hemorrhage
(ICH) brain injury induced by toxic blood components and subsequent neuroinflammation. The …

Molecular correlates of hemorrhage and edema volumes following human intracerebral hemorrhage implicate inflammation, autophagy, mRNA splicing, and T cell …

M Durocher, B Knepp, A Yee, G Jickling… - Translational stroke …, 2021 - Springer
… resulting in increased capillary permeability and brain edema following ICH [12, 36]. …
hemorrhagic transformation following delayed tPA administration in experimental ischemic stroke

Therapeutic hypothermia for intracerebral hemorrhage: Systematic review and meta-analysis of the experimental and clinical literature

TS Baker, J Durbin, Z Troiani… - … Journal of Stroke, 2022 - journals.sagepub.com
… hypothermia to treat intracerebral hemorrhage. A random-effects … , blood brain barrier
breakdown, cerebral edema, hematoma volume, … Other findings: Regional cerebral blood flow was …

Association between perihematomal perfusion and intracerebral hemorrhage outcome

A Morotti, G Busto, A Bernardoni, S Marini, I Casetta… - Neurocritical Care, 2020 - Springer
… images (panel A) and perihematomal perfusion mapping with cerebral blood flow (panel
B) in a patient with acute spontaneous intracerebral hemorrhage located in left temporal lobe …