… experiments and expected in the JIKI trial. Accordingly, a first … In addition to historical
preclinical data available from the … Ebola virus and treated with ascending doses of favipiravir. Left…

… treating influenza virus infections. In the setting of the pioneer Phase II JIKI trial, 126 patients
with acute Ebola virus disease … JIKI trial, favipiravir treatment was offered in the Coyah Ebola …

… FPV was also used in the therapy of Ebola virus disease (… patient group treated with the drug
and the historical patient group … fever virus, both in cell cultures and in experimental animal …

… trial for Ebola virus disease in Guinea. In a retrospective analysis of 124 patients with Ebola
virus disease in Sierra Leone, those treated … compared with historical controls treated with …

… -human primate model of Ebola virus disease. In this study, … antiviral efficacy in a historically
controlled trial (JIKI trial), but our … experiments conducted in a macaque model of Ebola Virus …

… Another trial of favipiravir treatment of an intranasal model of EVD in interferon … During the
JIKI trial, an unexpected drop in human serum titers of … experiment. This suggests that 8 days of …

… Small geographically isolated outbreaks have historically been … experimental therapy. In
2015, the Partnership for Research on … nonrandomized clinical trial (called the JIKI trial) was …

… , non-randomised trial with historical controls in which favipiravir … with confirmed Ebola virus
disease with a lower viral load (cycle … -infected patients of the JIKI trial reveals concentrations …

… and also a single-arm, controlled trial. This clinical trial is known as the JIKI trial, which …
in the survival of patients with EVD receiving favipiravir compared with controls [19]. Another …

… events observed during Ebola virus disease are linked to a … previous experiment in which
three doses of favipiravir were … for patients treated with favipiravir during the clinical trial [53] …