HLA expression in relation to HLA type in classic Hodgkin lymphoma patients

GW Tan, P Jiang, IM Nolte, K Kushekhar, RN Veenstra… - Cancers, 2021 - mdpi.com
human leukocyte antigen (HLA) alleles are strongly associated with susceptibility to classic
Hodgkin lymphoma (cHL)… on cHL tumour cells to lose HLA expression is associated with HLA

[PDF][PDF] HLA Expression in Relation to HLA Type in Classic Hodgkin Lymphoma Patients. Cancers 2021, 13, 5833

GW Tan, P Jiang, IM Nolte, K Kushekhar, RN Veenstra… - 2021 - academia.edu
human leukocyte antigen (HLA) alleles are strongly associated with susceptibility to classic
Hodgkin lymphoma (cHL)… on cHL tumour cells to lose HLA expression is associated with HLA

Interaction between ERAP alleles and HLA class I types support a role of antigen presentation in Hodgkin lymphoma development

P Jiang, RN Veenstra, A Seitz, IM Nolte, BG Hepkema… - Cancers, 2021 - mdpi.com
HLA class I, ie, endoplasmic reticulum aminopeptidase 1 (ERAP1) and ERAP2. We hypothesized
that ERAP and HLA class I type … and ERAP2 expression in tumor cells and cells in the …

Association of HLA diversity with the risk of 25 cancers in the UK Biobank

QL Wang, TM Wang, CM Deng, WL Zhang, YQ He… - …, 2023 - thelancet.com
… A lower risk of Hodgkin lymphoma was associated with the HLA class I … HLA diversity was
observed in the development of lung cancer, non-Hodgkin lymphoma and Hodgkin lymphoma. …

Checkpoint protein expression in the tumor microenvironment defines the outcome of classical Hodgkin lymphoma patients

K Karihtala, SK Leivonen… - Blood …, 2022 - ashpublications.org
course of classical Hodgkin lymphoma (cHL). We used gene … , HLA-DR expression did not
correlate with CD4 + T cell or … tissue, they can also be expressed in malignant cells. In cHL, …

Circulating tumor DNA predicts response in Chinese patients with relapsed or refractory classical hodgkin lymphoma treated with sintilimab

Y Shi, H Su, Y Song, W Jiang, X Sun, W Qian… - …, 2020 - thelancet.com
expression levels of PD-L1, PD-L2, major histocompatibility complex (MHC) class I and class
II in tumor [ … of tumor cell turnover, which reflects real-time tumor cell mortality, rather than …

Rosetting T cells in Hodgkin lymphoma are activated by immunological synapse components HLA class II and CD58

J Veldman, L Visser, M Huberts-Kregel… - Blood, The Journal …, 2020 - ashpublications.org
Hodgkin lymphoma (HL) characteristic is the tight adherence of rosetting CD4 + T cells to
Hodgkin tumor cells. … To address this, we developed a novel short-term in vitro coculture model …

Study on the inflammatory microenvironment of Epstein‒Barr virus-infected Hodgkin's lymphoma

H Li, B Li, X Li - 2024 - researchsquare.com
expression of MHC-I on tumour cells is a prerequisite for successful anti-PD-1/PD-L1 therapy
and that the expression of MHC-… , Chinese Medical Association, Chinese Working Group for …

Human Leucocyte Antigen (HLA) class I expression is an EBV-independent major determinator of microenvironment composition in classic Hodgkin Lymphoma and …

W Klapper, B Müller-Meinhardt, N Seifert, J Grund… - 2023 - researchsquare.com
… a T-cell immune response directed against the neoplastic cells, we investigate the immune
landscape of HL in relation to the expression of HLA … in Chinese classical Hodgkin lymphoma

HLA class II molecule HLA-DRA identifies immuno-hot tumors and predicts the therapeutic response to anti-PD-1 immunotherapy in NSCLC

J Mei, G Jiang, Y Chen, Y Xu, Y Wan, R Chen, F Liu… - BMC cancer, 2022 - Springer
expression can also benefit from immunotherapy [14, 15]. In summary, it can be found that the
PD-L1 expression level of tumor cells is … (Shanghai, China). A total of 75 NSCLC and para-…