[HTML][HTML] Mechanism of lysine oxidase-like 1 promoting synovial inflammation mediating rheumatoid arthritis development

J Hu, X Liu, Q Xu, M Zhu, S Wang, K Quan… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… Basement membrane-associated differential genes between … the expression levels of LOXL1
in synovial tissues of patients … as IL-6, INOS and COX2 in synovial tissues was detected by …

[HTML][HTML] PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study

S Shrestha, MJ Kim, M Eldridge, ML Lehmann… - Journal of …, 2020 - Springer
… counted as expressing Cox2 or Eno2 mRNA if two or more … It should be noted that these
differential responses might be … infiltration of leukocytes into the synovial membrane, a classic …

Increased nerve growth factor expression in the synovial tissues of patients with rotator cuff tears

R Tazawa, T Kenmoku, K Uchida… - Molecular …, 2021 - journals.sagepub.com
cyclooxygenase-2 (COX-2) expression levels (using mRNA and protein expression) in synovial
membrane tissuesCOX2 expression between the subacromial bursa and rotator interval …

Sirtuin 6 ameliorates arthritis through modulating cyclic AMP-responsive element binding protein/CCN1/cyclooxygenase 2 pathway in osteoblasts

SK Lin, HW Wang, CT Shun, CN Yang… - Journal of Bone and …, 2023 - Springer
… [2], its contribution to the induction of COX2 in inflammatory arthritis has not been addressed.
Our experiments disclosed that CCN1 is able to induce COX2 expression … to synovial tissue

Compatibility of Achyranthes bidentata components in reducing inflammatory response through Arachidonic acid pathway for treatment of Osteoarthritis

Z Li, D Ma, L Peng, Y Li, Z Liao, T Yu - Bioengineered, 2022 - Taylor & Francis
… of synovial tissue showed aligned synovial tissue cells in the … analysis of the differential
expressed metabolites showed … verified the down-regulated expression of PEG2 and COX2 in the …

[HTML][HTML] Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis

Y Wu, H Wang, Y Huo, B Yan, H Honda, W Liu… - Journal of Biological …, 2023 - ASBMB
… Knockdown of DEC1 in human RA synovial fibroblast cell … genes such as COX-2 (cyclooxygenase-2),
OB-cadherin (… in the synovial tissues, especially in the hyperplasic synovium

Inflammation: Biochemistry, cellular targets, anti-inflammatory agents and challenges with special emphasis on cyclooxygenase-2

B Kaur, P Singh - Bioorganic Chemistry, 2022 - Elsevier
… Chronic inflammation and proliferation of synovial tissue present in the synovial lining of
joints results in the pannus formation by the process of hyperplasia that invades the cartilage …

[HTML][HTML] Construction and analysis of a lncRNA–miRNA–mRNA competing endogenous RNA network from inflamed and normal synovial tissues after anterior cruciate …

X Xiao, X Yang, S Ren, C Meng, Z Yang - Frontiers in Genetics, 2022 - frontiersin.org
Frontiers | Construction and analysis of a lncRNA–miRNA–mRNA competing endogenous
RNA network from inflamed and normal synovial tissues after anterior cruciate ligament and/…

Synovial tissue metabolomics analysis of the therapeutic effects of stir-fried Xanthii Fructus on rheumatoid arthritis in rats

Z Zhang, J Zhang, S Zhao, T Peng, M Zhang… - … of Chromatography B, 2023 - Elsevier
… Heat map of differential metabolite content in synovial tissue. Note: Red represents … Palmitic
acid can lead to cartilage deterioration by inducing the expression of cyclooxygenase-2 and …

The synovium of human osteoarthritic joints retains its chondrogenic potential irrespective of age

EB Hunziker, N Shintani, M Haspl… - Tissue Engineering …, 2022 - liebertpub.com
… bovine synovial tissue as a paradigm for human synovial … -2/TGF-β1(to prevent terminal
differentiation to chondrocyte hypertrophy and matrix mineralization 16 ), the differentiated tissue